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LIVE POLIO IRUS VACCINES

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Development and Persistence of Polio Antibodies in Young Adults 239<br />

eases. The analysis of all potential non-specific<br />

factors should be the first step in this investigation.<br />

REFERENCES<br />

1. Ward, R., Chang, C., and Rader, D.: Importance<br />

of optimum amounts of virus to demonstrate<br />

neutralizing antibody rise in convalescent<br />

poliomyelitis sera. Proc. Soc. Exp. Biol.<br />

90: 162-165, 1955.<br />

2. Brunner, K. T., and Ward, R.: Differences in<br />

stability of antigen-antibody complexes formed<br />

with poliovirus and acute and convalescent<br />

phase human sera. J. Immun. 83: 405-410,<br />

1959.<br />

3. Sabin, A. B.: Properties of attenuated polioviruses<br />

and their behavior in human beings.<br />

New York Academy of Sciences, Monograph<br />

no. 5: 113-127, 1957.<br />

4. Vonka, V., Zácek, K., and Duben, J.: Paper<br />

presented at the International Symposium on<br />

Live Poliovirus Vaccine, Moscow, May 1960.<br />

5. Gard, S.: Neutralization of Theiler's virus.<br />

Acta Path. Microb. Scand. 37: 21-30, 1955.<br />

6. -- Immuno-inactivation of poliovirus.<br />

Arch. ges. Virusforsch. 7: 449-460, 1957.<br />

7. Skovránek, V., Zácek, K., Vonka, V., Adam,<br />

E., Adamová, V., Burian V., and Vojtová, H.:<br />

Field trial with Sabin's live poliovirus vaccine<br />

in Czechoslovakia-1958-1959. In: Live Poliovirus<br />

Vaccines, First International Conference.<br />

Scient. Pub. no. 44 of the Pan American<br />

Health Organization, pp. 530-571, 1959.<br />

8. Gelfand, H. M., LeBlanc, D., Fox, J. P., and<br />

Potash, L.: Studies on the development of<br />

natural immunity to poliomyelitis in Louisiana.<br />

III. The serological response to commercially<br />

produced "Salk vaccine" of children<br />

totally or partially susceptible to poliovirus infection.<br />

Am. J. Hyg. 70: 303-311, 1959.<br />

9. Black, F. L., and Melnick, J. L.: Appearance<br />

of soluble and cross-reactive complement-fixing<br />

antigens on treatment of poliovirus with<br />

formalin. Proc. Soc. Exp. Biol. 89: 353-355,<br />

1955.

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