LIVE POLIO IRUS VACCINES

222
Safety-Field Evidence of Safety
POLIOYIRUS TYPE I POLIOVIRUS TYPE 11 FOLIOVIRfS TYPE III
Pre- Post- Pre- Post- Pre- Post-
Cord Feeding Fooding Cord Pedíng Feeding Cord Feeding Feeding
Be irth 3-6 Nos. 4-7 Nos. 12 Mos. .irth urth 3-6 Mos. 4-7? os. -12 Mos. 3-6 os. 4-7 Nos.. t 12 No
>1024 _o. . X 4.X xxxx 1
oo
o o
1024 xx x xx x
o 000 o o
6512 xxxx x x x
x x ..
0 0 0 0 o
o
xx
xx
12 x xxxx xxx xxx xxx xx xxx
o.. '4 o + + UUI00 000 xxx +
0 x 000 + 0o
o c
0.5
o
o
26 xx xxxx x xx. x xx xxx
x o = xxx.. xx o x xxxx x xix o x
8 O 00 + D + * _oo -4-0 00 - o D
~~+1:1024
1:1024
1:512
1: 256
1:128
1:64
1:32
1I8
1'4
1:1024. The Types 1 and 2 titers in spite of
vaccination continued to decay at a rate compatible
with a half-life of 37 days. At 237 days
of age a larger dose of vaccine (2.0 cc.) was fed.