LIVE POLIO IRUS VACCINES

416 Effcacy-Field Evidence
TABLE 3.
COMPARATIVE DATA OF SEROLOGIC SURVEY OF THE VACCINATED WITH LIQUID TRIVALENT
VACCINE AND TRIVALENT VACCINE INCORPORATED INTO POMADKA-CANDY
(Antibody Patterns)
TRIVALENT LIQUID LIVE VACCINE
(ESTONIA, 1959, DOBROVA, I.N.)
TRIVALENT LIVE VACCINE INCORPORATED
INTO POMADKA-CANDY (1959, FLEER, G.P.)
TOTAL WITH ANTIBODY
TOTAL WITH ANTIBODY
BEFORE AFTER VACCINATION BEFORE AFTER VACCINATION
VACCINATION
VACCINATION
1 + 2 + 3+ 1+ 2 + 3+
000 000
13 pers. 8 10 10 19 pers. 13 16 8
26.5% 61.5 78.9 76.9 43.1% 68.4 84.2 42.1
00+ 00+
4 pers. 3 3 4 3 pers. 3 2 3
8.2% 75.0 75.0 100.0 6.8% 100.0 66.6 100.0
0+0 0+0
10 pers. 8 10 7 4 pers. 4 4 3
20.4% 80.0 100.0 70.0 9.0% 100.0 100.0 75.0
0++ O++
12 pers. 9 12 12 6 pers. 6 6 6
24.5% 75.0 100.0 100.0 13.6% 100.0 100.0 100.0
+00 +00
4 pers. 4 4 3 3 pers. 3 3 1
8.2% 100.0 100.0 75.0 6.8% 100.0 100.0 33.3
+O+
+O+
3 pers. 3 3 3 4 pers. 4 4 4
6.1% 100.0 100.0 100.0 9.0% 100.0 100.0 100.0
++0 ++0
3 pers. 3 3 3 5 pers. 5 5 5
6.1% 100.0 100.0 100.0 11.3% 100.0 100.0 100.0
49 38 45 41 44 38 40 29
100.0% 77.5 91.8 83.7 100.0% 86.4 90.9 66.0
Increase of antibody
1 + +57.1%
2+ +40.8%
3 + +44.9%
of dragée-candy (Tables 1, 2, 3, 4). Tests for
the establishment and immunogenicity of the live
vaccine in dragée-candy, carried out in 1959 by
G. P. Fleer in the town of Klin in the Moscow
region, showed quite satisfactory results, which
could be favorably compared with those obtained
Increase of antibody
1 + +59.2%
2 + +50.0%
3+ +36.5%
in immunization with liquid live vaccine (see
Table 5 and Fig. 1).
E. E. Ashmarina and S. G. Drozdov (1960)
confirmed a high degree of establishment in children
of monovaccines fed in the form of dragéecandy
(Table 5).