LIVE POLIO IRUS VACCINES

274
Efficacy-Laboratory Evidence
TABLE 6A. VIROLOGICAL FINDINGS AND SEROLOGICAL RESPONSE TO ORAL POLIOMYELITIS VACCINE
IN INFANTS WITH PRE-FEEDING ENTEROVIRUS IN THEIR STOOLS
PRE-FEEDING ENTEROVIRUS IDENTIFIED
POST- F(éD/iN v PtOO /u'O¿4T/ONJ' PPE I. 4-&O Y6EV/NC
Cé/íLD PRE-TfiO/lCIG r Wr wFKVY / ;rRV,4J gNT/6ODnY/rER TO
Nio ETIEROV/I I . 3 4 _ Tt T3
40 Cox.~'S 7E T3 rs Ar. )· ,
Cox C&5 CoKx 5 T 3 4, 256
8 Cox B5 _ 75 /6 /L.
Cox_ 5 64 6,
._ __ _ _/6 0o
/49 Cox 95 T , f 7- T. 3 T 3 L4
/33 Cox A9 TI , T _ O O
/6/ C11/c4o _ 7; 3 13 r4 o
64, 256
Upper numbers-pre-feeding, lower numbers-post-feeding.
post-feeding stool specimens. Type 1 poliovirus
only was excreted and a somewhat lower antibody
response was found to the type excreted. Infant
No. 149 also excreted Types 1 and 3 in the postfeeding
stool specimens, but responded serologically
only to Type 3 and failed to show antibodies
to Type 1 poliovirus. Child No. 133 excreted
Type 3 in one stool specimen but Type 1 in all
four stool specimens. The serological response,
as observed, was mainly to Type 1 and very low
to Type 3 poliovirus. Infants Nos. 101 and 18
excreted both Types 1 and 3 and showed a comparatively
high antibody titer to both.
Table 6b illustrates results obtained on seven
TABLE 6B. VIROLOGICAL FINDINGS AND SEROLOGICAL RESPONSE TO ORAL POLIOMYELITIS VACCINE
IN INFANTS WITH PRE-FEEDING ENTEROVIRUS IN THEIR STOOLS
PRE-FEEDING
ENTEROVIRUS UNIDENTIFIED
| PO.T. ~/tED/SN