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LIVE POLIO IRUS VACCINES

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24. A SMALL-SCALE TRIAL WITH <strong>LIVE</strong> <strong>POLIO</strong>MYELITIS VACCINE<br />

IN AN ISOLATED ISLAND COMMUNITY<br />

N. OKER-BLOM, HELENA STRANDSTROM, AND A. W. ERIKSSON<br />

Department of Virology, University of Helsinki, Finland<br />

Dr. OKER-BLOM (presenting the paper): After<br />

several days of listening to the results of largescale<br />

trials and mass vaccinations with all the<br />

three types of live attenuated poliovirus strains,<br />

one wonders whether it is at all worthwhile to<br />

present the results of a trial including only 200<br />

persons.<br />

However, some preliminary data concerning<br />

the 1958 Sottunga trial were presented here last<br />

year, and as the trials have now been extended<br />

and finished, it may be justifiable to give the<br />

final results of these trials now, although these<br />

may probably be merely of academic interest.<br />

MATERIALS AND METHODS<br />

Selection of Study Population<br />

The region chosen for the trial was the fairly<br />

isolated Sottunga Island in the middle of the<br />

Aland Archipelago (Fig. 1), which lies west of<br />

the Finnish mainland and east of Sweden, with<br />

the gulf of Botnia to the. north and the Baltic<br />

sea to the south.<br />

The whole Aland Archipelago has a population<br />

of 21,000 persons. Sottunga Island has a<br />

registered population of only 253 persons and<br />

FIG. 1<br />

533

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