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LIVE POLIO IRUS VACCINES

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Virologic, Serologic Investigations of Immunization With Sabin's Strains 249<br />

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1<br />

II<br />

III<br />

11 III IV V-VIII weeks<br />

Fim 1. Excretion of Types 1, 2, 3 vaccine viruses by children immunized with trivalent<br />

live vaccine from Sabin's strains.<br />

TABLE 15.<br />

ESTABLISHMENT OF TYPE 1 VACCINE V<strong>IRUS</strong> IN PERSONS IMMUNIZED WITH TRIVALENT <strong>LIVE</strong><br />

VACCINE, IN RELATION TO THE PRESENCE OR ABSENCE OF <strong>POLIO</strong>MYELITIS ANTIBODY<br />

ANTIBODY<br />

CHILDREN<br />

No. tested<br />

Excreted virus<br />

Per cent<br />

1+2+3+<br />

33<br />

9<br />

27<br />

-------<br />

the number of triple positive children increased<br />

by 56.5 per cent, while in children's home L. in<br />

the Moscow region only by 23.1 per cent. Summary<br />

data on the increase in the number of children<br />

with antibody to all the three types of<br />

poliovirus vaccinated during summer were only<br />

4.6 per cent lower than those obtained in winter<br />

vaccination with trivalent vaccine. (Estonian,<br />

SSR data by I. H. Dobrova). The increase in the<br />

number of children developing Type 2 antibody<br />

differed from that observed in the winter only by<br />

5.4 per cent. A greater difference between the

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