LIVE POLIO IRUS VACCINES

Virologic, Serologic Investigations of Immunization With Sabin's Strains 253
1,111
BEFORE VACCINATION
ONE MONTH AFTER
E
Type
FIc. 4.
1 Type II Type Type
Antibody patterns before vaccination and one month after one feeding with trivalent live
vaccine from Sabin's strains (Moscow region).
III
TABLE 20.
INCREASE IN THE NUMBER OF CHILDREN POSSESSING ANTIBODY TO THE THREE TYPES OF
POLIOVIRUS ONE MONTH AFTER ONE FEEDING WITH TRIVALENT LIVE VACCINE
NUMBER
OF
CHILDREN
INCREASE OF NUMBERS OF CHILDREN WITH ANTIBODY TO
3 types
Type 1
Type 2 Type 3
No.
No.
No.
No.
Moscow region 133 91 68.4 57 42.9 78 58.7 55 41.4
(towns and
districts)
L. children's 39 9 23.1 16 41.1 16 41.0 12 28.1
home
Karaganda region 51 28 54.9 16 31.4 13 25.3 13 25.5
Moscow and 223 128 56.6 89 39.9 79 35.4 80 35.9
Karaganda
regions
(summary data)
Estonian SSR 49 30 61.2 28 57.1 20 40.8 22 44.9
(data by I. N.
Dobrova)
developed Type 2 antibody
greater. The lowest titers
titers of 1:256 or
after one feeding
were observed with Type 3 antibody: half of the
children had Type 3 antibody in titers 1:16.
Analysis of age
(Table 22) showed
distribution of antibody
that one month after one
feeding of trivalent live vaccine Types 1 and 3,
antibodies were produced in a higher portion of