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LIVE POLIO IRUS VACCINES

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422<br />

Efficacy-Field Evidence<br />

taneous mass immunization with trivalent live<br />

vaccine during a period of steep rise in poliomyelitis<br />

incidence in Tashkent in 1959, was<br />

definite proof of the possibility of considerably<br />

reducing poliomyelitis incidence within five<br />

weeks, this being due to the effect of interference<br />

by the vaccine virus with the epidemic process<br />

and to progressive immunization of susceptible<br />

population groups.<br />

In conclusion, I should like to call attention<br />

to the fruitful international cooperation in the<br />

matter of live poliovirus vaccine, which has<br />

existed between scientists of the U.S.A., the<br />

Soviet Union, Czechoslovakia, Hungary, German<br />

Democratic Republic, People's Republic of<br />

China, Bulgaria, and other countries on the basis<br />

of broad exchange of scientific information, personal<br />

contacts, mutual exchange of results of<br />

research work, and friendly support.<br />

All that has been done heretofore is, undoubtedly,<br />

only a promising start of regular future<br />

international cooperation among medical scientists<br />

towards the speediest eradication of certain<br />

infectious diseases or, at least, sharp reduction<br />

of their number.<br />

TABLE 8. DATA ON <strong>LIVE</strong> <strong>POLIO</strong>V<strong>IRUS</strong> VACCINE DISTRIBUTION IN 1960<br />

(January-May. inclusive)<br />

REPUBLICS<br />

TYPE 1<br />

NUMBER OF DISTRIBUTED INOCULATION DOSES IN THOUSANDS<br />

I I I<br />

MONO<strong>VACCINES</strong><br />

INCLUDING<br />

TRIVACCINE TOTAL FOR PRIMARY<br />

TYPE 2 TYPE 3<br />

VACCINATIONS<br />

RSFSR<br />

Ukrain. SSR<br />

Kazakhstan<br />

Uzbekistan<br />

Byelorussia<br />

Georgia<br />

Azerbaijan<br />

Moldavia<br />

Lithuania<br />

Latvia<br />

Kirghiz SSR<br />

Tajikistan<br />

Armenia<br />

Turkmenia<br />

Estonia<br />

39,407.3<br />

12,080.6<br />

2,294.0<br />

3,176.0<br />

3,000.0<br />

1,500.0<br />

1,404.0<br />

600.0<br />

750.0<br />

610.0<br />

800.0<br />

750.0<br />

550.0<br />

882.0<br />

67,819.9<br />

34,657.5<br />

9,206.3<br />

200.0<br />

3,000.0<br />

30.0<br />

773.6<br />

902.0<br />

48,769.4<br />

37,610.4<br />

9,466.6<br />

200.0<br />

2,976.0<br />

772.0<br />

800.0<br />

51,825.0<br />

4,409.8<br />

6,454.6<br />

3,502.7<br />

4,406.0<br />

1,699.2<br />

1,557.0<br />

900.0<br />

2,000.0<br />

452.4<br />

1,102.0<br />

1,102.2<br />

928.0<br />

898.0<br />

29,411.9<br />

116,085.0<br />

37,208.1<br />

5,796.7<br />

7,982.0<br />

8,976.0<br />

3,199.2<br />

2,991.0<br />

1,500.0<br />

2,750.0<br />

2,608.0<br />

1,902.0<br />

1,852.2<br />

1,702.0<br />

1,478.0<br />

1,780.0<br />

___ ~ __ _ _/_<br />

197,810.2<br />

40,907.3<br />

14,504.0<br />

3,600.0<br />

4,400.0<br />

3,000.0<br />

1,500.0<br />

1,434.0<br />

1,100.0<br />

2,000.0<br />

1,000.0<br />

1,100.0<br />

1,100.0<br />

900.0<br />

900.0<br />

898.0<br />

78,343.3<br />

TABLE 9. REDUCTION OF PARALYTIC <strong>POLIO</strong>MYELITIS INCIDENCE IN Moscow IN THE SECOND HALF OF<br />

1959 AMONG CHILDREN VACCINATED WITH <strong>LIVE</strong> VACCINE<br />

GROUPS OF CHILDREN<br />

UNDER 15 YEARS<br />

OF AGE<br />

NUMBER OF<br />

CHILDREN<br />

IN THOUS.<br />

NUMBER OF<br />

CASES<br />

INDEX PER<br />

100,000<br />

RATIO OF<br />

INDICES<br />

Vaccinated 1,058 59 5.6<br />

Unvaccinated 392 203 51.8<br />

1:9.25

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