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LIVE POLIO IRUS VACCINES

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Vaccination and Challenge-Poliomyelitis in Nicaragua<br />

551<br />

FIGURE 3<br />

NOTIFIED CASES OF PARALYTIC <strong>POLIO</strong>MYELITIS, BY WEEK OF ONSET, IN THE DEPARTMENT<br />

MANAGUA AND ALL OF NICARAGUA DURING EPIDEMIC PERIOD 1959-1960<br />

1959<br />

NOV. |<br />

DECEMBER<br />

1960 M N T H<br />

JANUARY [ FEBRUARY ¡ MARCH<br />

i i , 1 I i i . i I<br />

1 APRIL ¡ MAY<br />

OF<br />

-24<br />

24-<br />

22-<br />

- 22<br />

20-<br />

20<br />

18-<br />

18<br />

16-<br />

16<br />

u<br />

o<br />

i<br />

'1<br />

z<br />

14-<br />

2<br />

I<br />

14 ,<br />

o<br />

12 -<br />

10 z<br />

12- ... . - 0 : - ';. _<br />

8<br />

6<br />

10<br />

8~~~~~~~~~~~~~~~~<br />

4<br />

n 5 o 1q17 11 ~ T9<br />

4 ' 51 S 521 1 2 3 14 ¡ 5 61 7 8<br />

ti 22 -2/NOV /59<br />

WEEKS<br />

9 ' 10 11 12 13 1 14 15<br />

10 l./MAy/6O<br />

o<br />

] IN THE DEPARTMENT OF MANAGUA<br />

:] IN ALL OF NICARAGUA<br />

1, 3, and 4). Four deaths were recorded, giving<br />

a case fatality rate of 1.8 per cent versus 7.1<br />

per cent in 1958.<br />

Thirteen of the 16 departments of Nicaragua<br />

were involved in the epidemic. Of the 92 cases<br />

in Managua, 88 were recorded in the City of<br />

Managua and four in other communities of the<br />

Department (Fig. 2). As in 1958, the highest<br />

incidence of poliomyelitis in the rest of the coun-<br />

try was observed in the Departments of Chinandega,<br />

León, and Masaya.<br />

If we consider collectively the 225 cases reported<br />

in the country from 1 January 1959 to<br />

14 May 1960 (Table 3), it can be noted that as<br />

in 1958, 75 per cent of these cases were in<br />

children less than two years of age. However,<br />

the proportion of cases in this age group in<br />

Managua in 1959-1960 was 74 per cent versus

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