LIVE POLIO IRUS VACCINES

252 Efficacy-Laboratory Evidence
TABLE 18. ANTIBODY RESPONSE IN SERONEGATIVE CHILDREN ONE MONTH AFTER ONE FEEDING
WITH TRIVALENT LIVE VACCINE
ANTIBODY DEVELOPMENT IN GROUPS OF "NEGATIVE"
CHILDREN
10 2 ° 3 °
10 20 3 ° TYPE 1 TYPE 2 TYPE 3
No. % No. % No. % No. % No. % No. %
Moscow region 57* 73.1 82 89.1 60 69.8 19 61.3 24 77.1 18 58.1
(towns and 78 92 86 31 3 31
districts)
L. children's 10 50.0 15 75.0 11 28.9 7 36.8 15 78.9 4 21.0
home 32 20 38 19 19 19
Karaganda 19 59.4 15 68.2 15 55.5 1 10.0 4 40.0 5 50.0
region 32 22 27 10 10 10
Moscow and 92 64.8 85 80.2 86 56.9 27 45.0 43 71.7 27 45.0
Karaganda 142 106 151 60 60 60
regions
(summary
data)
Estonian SSR 28 71.8 20 83.3 8 73.3 8 61.5 10 76.9 10 76.9
(data by I. N. 39 24 30 13 13 13
Dobrova)
,57 í---57 of 78 children formerly Type 1 negative, developed Type I antibody.
TABLE 19. ANTIBODY PATTERNS BEFORE VACCINATION AND ONE MONTH AFTER ONE FEEDING WITH
TRIVALENT LIVE VACCINE FROM SABIN STRAINS IN 223 CHILDREN WITH ANTIBODY DEFICIENCY
BEFORE VACCINATION
ONE MONTH AFTER
No. OF CHILDREN
No. OF CHILDREN
000 60 26.9 9 4.0
00+ 12 5.4 5 2.2
0+0 37 16.6 25 11.2
0++ 33 14.8 14 6.3
+00 7 3.1 8 3.6
+0+ 27 12.1 5 2.2
++0 47 21.1 29 13.0
_ 0 12 _5
0 0 128
57.3