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ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

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the study of Polikeit et al. [10]. The properties of the ligament elements were taken from to<br />

literature ([2, 11, 12]) and modified by adding toe region.<br />

The FE model representing the average vertebra geometry, disc height and lordotic angle was<br />

used to validate the simulation procedures. For this purpose, the model was loaded with a<br />

2500 N compressive follower load to compare its response to the in-vitro test results reported<br />

be Eberlein et al [13]. In addition, the predicted range of motion from simulation results was<br />

also compared to the in-vitro results reported in Bowden et al. [14] by loading the models<br />

with a 7.5 Nm pure bending moment in flexion and extension, respectively.<br />

For investigating the influence of disc anatomy on the mechanical response of the IVD, and<br />

for identifying the window of uniaxial mechanical properties for a candidate implant material,<br />

nine FE-model geometries were created (see fig. 1). This was done by varying the disc size in<br />

the disc plane within the range for lumbar vertebra geometries reported by Panjabi et al. [5].<br />

The disc height and lordotic angle were also varied within the range of values reported by<br />

Abuzayed et al. [6]. All models were investigated under four different load cases, generated<br />

by loading the vertebrae with a 7.5 Nm moment about different axis (flexion, extension,<br />

lateral bending and torsion respectively) in addition to a follower load of 1000 N<br />

(compression). The load was applied in 10 incremental steps until maximum loading was<br />

achieved. Principal stresses and principal strains were sampled for all annulus elements over<br />

the full range of model geometries and loading cases to assemble representative ranges<br />

defining appropriate candidate implant material properties.<br />

Fig.2. Principal stresses vs. principal strains for all annulus elements for all load steps and all<br />

load cases for the nine different vertebra geometries simulated.

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