ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

imaging. Basing on the image dataset the surgeon identifies the region of cancer
resection and geometry of individual bioimplant (see fig. 1). First stage of bioimplant
production is to generate a custom-made scaffold with geometry designed in the
computer system. On the scaffold there are plotted growth factors and developed stem
cells grafted from the patient to develop a product of tissue engineering, a bioimplant
which could be bioacceptable. Intraoperatively the surgeon resects the tumor according
to the designed plan. After the precise resection, during the same surgical procedure the
bioimplant is implanted under control of navigation using the developed software.
3.2 Planning of the surgery
Fig. 1. Idea of bone reconstruction after tumor resection
The developed system enables reading DICOM data and binary or ASCII STL files.
A. The tumor identification
In the first stage, the surgeon manually identifies the contours of tumor on the scans (CT
or MRI examination) (see fig. 2). The contours are saved in a file and may also be read
during next analyses. Basing on the contours a 3D model of tumor tissue is generated.
Fig. 2. The tumor identification