ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

In Fig.3, the distribution of the aggregated platelets along the lesion is depicted. By a
good comparison with all previous works, the same pattern of distribution was achieved
as in [2,5,12].
6. Conclusion
In conclusion, it can be pointed out that the model incorporates the important features of
the previous models proposed in [2,5,6] and added more physiological concepts such as
the CDR equation and the drag-dependent detachment function. In this study, we also
implemented a better approach to shed light on colloidal characteristics of blood
components in microcirculation.
8. REFERENCES
1. High, KA, Roberts, HR, “Molecular Basis of Thrombosis and Hemostasis”, 1995,
Taylor and Fransis, pp. 35-50
2. Sorensen, E. N., Burgreen, G. W., Wagner, W. R., & Antaki, J. F. (1999).
Computational simulation of platelet deposition and activation: I. Model
development and properties. Ann. Biom. Eng., 27(4), 436-48.
3. Longest, W. P., & Kleinstreuer, C. (2003). Comparison of blood particle
deposition models for non-parallel flow domains, J. of Biomech.,36(3), 421-430.
4. Ouared, R., & Chopard, B. (2005). Lattice Boltzmann Simulations of Blood Flow:
Non-Newtonian Rheology and Clotting Processes. J. Stat.Phys,121(1-2), 209-221.
5. Filipovic, N., Kojic, M., & Tsuda, a. (2008). Modelling thrombosis using
dissipative particle dynamics method. Philosophical transact. Series A, Math.,
phys., and eng. sciences, 366(1879), 3265-79
6. Pivkin, I. (2006). Algorithms for Continuum and Atomistic Modeling of Blood
Platelet Phenomena, Brown.
7. Groot, R. D., & Warren, P. B. (1997). Dissipative particle dynamics: Bridging the
gap between atomistic and mesoscopic simulation, J. of Chem. Phys., 107(11),
4423.
8. Pivkin, I. V., & Karniadakis, G. E. (2005). A new method to impose no-slip
boundary conditions in dissipative particle dynamics. J. Comp. Phys, 207(1), 114-
128.
9. Whittle, M., Murray, B. S., & Dickinson, E. (2000). Simulation of Colloidal
Particle Scattering: Sensitivity to Attractive Forces. J. col. and interf. Sci., 225(2),
367-377.
10. Chen, S., Phan-Thien, N., Khoo, B. C., & Fan, X. J. (2006). Flow around spheres
by dissipative particle dynamics. Phys. of Fluids, 18(10), 103605
11. W A Khan, J R Culham, M. M. Y. (2005). Fluid Flow Around and Heat Transfer
From an Infinite Circular Cylinder. J. Heat Trans., 127(July).
12. Hubbell, J. A., & McIntire, L. V. (1986). Visualization and analysis of mural
thrombogenesis on collagen, polyurethane and nylon. Biomaterials, 7(5), 354–360.
13. Goodman, P. D., Barlow, E. T., Crapo, P. M., Mohammad, S. F., & Solen, K. a.
(2005). Computational Model of Device-Induced Thrombosis and
Thromboembolism. Ann. Biom. Eng., 33(6), 780-797.