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ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

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and 2b illustrate the WSS magnitude (clipped at 0.5 Pa), together with the<br />

corresponding histological sections. The percentage restenosis was calculated from<br />

histomorphometric evaluation. Results for the stent show that both inlet and outlet<br />

regions of the stent display a large zone of low flow and a corresponding region of the<br />

neointimal growth.<br />

Figure 2: A. Histological cross-sections of stented vessel and histomorphometric evaluation of the<br />

percentage restenosis; B. Numerical representation of WSS magnitude along slice surface. Black dashed<br />

lines in proximal and distal slices indicate regions with higher arterial WSS (>0.3 Pa) and lower NIH.<br />

Figure 3a shows the oxygen mass fraction concentration iso-contour plots with the Sh<br />

number as calculated in Table 1 using equation (1) and the average characteristic<br />

diameter at each of the selected cross-sections. Preliminary calculations for Sh, (Table<br />

1) were performed to investigate if the strut distribution pattern influences the overall<br />

oxygen transport. Figure 3b displays the helicity iso-contours which show dean vortices<br />

within two locations (proximal and middle) of the stented vessel domain.<br />

Figure 3: A. Oxygen concentration iso-contours in the three cross-sections with corresponding Sh<br />

numbers. Variations in concentration occur at the arterial wall adjacent to the strut locations; B. Helicity<br />

contours displayed at three corresponding locations within the stented geometry.

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