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ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

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direction at knee extension, placing it in a position where it becomes “wedged” between<br />

the femur and tibia during knee flexion. Contact pressures on the medial side<br />

intercondylar imminence increase with removal of the ACL (Fig. 6), indicating that the<br />

geometric constraint of the imminence is taking more load in the absence of the<br />

ligament constraint. The flexion angle for the three natural simulations did not change.<br />

The magnitude of the muscle forces did change slightly for muscles crossing the knee,<br />

but the patterns of the muscles forces did not change with increasing ACL deficiency.<br />

a.) b.) c.)<br />

Figure 5: Tibia plateau during forward dynamics simulation of the natural model at<br />

maximum flexion for the intact ACL (a.), partial ACL transection (b.), and full ACL<br />

transection(c.). The black arrows point to subluxation of the lateral meniscus.<br />

Figure 6: Predicted contact pressures on the medial tibia plateau during<br />

forward dynamics simulation of the natural model at maximum flexion for the<br />

intact ACL (a.), partial ACL transection (b.), and full ACL transection (c.).<br />

5. REFERENCES<br />

a.) b.) c.)<br />

[1] B. J. Fregly, T. F. Besier, D. G. Lloyd, S. L. Delp, S. A. Banks, M. G. Pandy, and D.<br />

D. D'Lima, "Grand challenge competition to predict in vivo knee loads," Journal<br />

of Orthopaedic Research, vol. In Press, <strong>2012</strong>.<br />

[2] A. Erdemir, S. McLean, W. Herzog, and A. J. van den Bogert, "Model-based<br />

estimation of muscle forces exerted during movements," Clin Biomech (Bristol,<br />

Avon), vol. 22, pp. 131-54, Feb 2007.<br />

[3] T. M. Guess, H. Liu, S. Bhashyam, and G. Thiagarajan, "A multibody knee model<br />

with discrete cartilage prediction of tibio-femoral contact mechanics," Comput<br />

Methods Biomech Biomed Engin, Oct 4 2011.<br />

[4] T. M. Guess, G. Thiagarajan, M. Kia, and M. Mishra, "A subject specific multibody<br />

model of the knee with menisci," Med Eng Phys, vol. 32, pp. 505-15, Jun 2010.<br />

[5] I. Lifemodeler, LifeMOD Manual, 2010.

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