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ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

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Fig. 1 Semicircular canal structure and function 6<br />

A stereocilia projecting from the hair cells are covered by a gelatinous substance in<br />

otoconia. The BPPV is caused by the otoilths coming apart by any reason. That is the<br />

result from abnormal stimulation of the cupola within any of the three semicircular<br />

canals by free-floating otoliths (canalithiasis) or otoliths adhered to the cupula<br />

(cupulolithiasis). A typical symptoms and signs of BPPV are motion sickness and<br />

nystagmus. 4, 5 The three semicircular canals lie at right angles to each other and occupy<br />

three different planes in space. Two of them, the anterior canal and the posterior canal,<br />

stand vertically, whereas the third, the lateral canal, is horizontal. The most common<br />

type of BPPV is caused by the involvement of the posterior semicircular canal (PSC),<br />

but horizontal semicircular canal (HSC) BPPV accounts for approximately 10% to 20%.<br />

PSC-BPPV has a good resolution rate of over 90% on average after proper canalith<br />

repositioning treatment. A HSC benign paroxysmal positional vertigo was first reported<br />

in 1985, after a lot of research on diagnosis and treatment had been reported. Many<br />

ways of treatment method have been reported in clinical trials which show meaningful<br />

good results. However, the success rate is approximately 60%~90%; this value does not<br />

give relief to patient. 3<br />

Fig.2 Canalithiasis and cupulolithiasis in benign paroxysmal positional vertigo. 7<br />

In this work, the computational simulation has been carried out for Benign Paroxysmal<br />

Positional Vertigo (BPPV) disease in semicircular canals of the vestibular apparatus.<br />

The 2-D FSI Model of semicircular canals in BPPV situation has been developed in the<br />

finite element software COMSOL 4.2a and focus is on horizontal semicircular canal<br />

which detects parallel movement.

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