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ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

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compared by overlaying the real data to drawn stent.<br />

2.2. Mesh Generation and Boundary Condition and Post Processing<br />

CFD analysis were conducted using AcuSolve FE-Based CFD Solver (AcuSim Inc/<br />

Altair Inc., USA) . Transient boundary conditions were applied on both the inlet and<br />

outlet similar to [6]. Inlet boundary conditions was taken as the time varying nodal<br />

velocity profile as to Womersley Flow assumption before the inlet, given as<br />

u<br />

n<br />

x, t<br />

C<br />

0<br />

<br />

<br />

<br />

Re<br />

<br />

<br />

k<br />

max<br />

<br />

k1<br />

J0<br />

1<br />

Ck<br />

<br />

J<br />

2 2<br />

<br />

1<br />

3<br />

ki<br />

3/<br />

2 ki<br />

x<br />

3/<br />

2<br />

0ki<br />

3/<br />

2<br />

J1ki<br />

3/<br />

2<br />

J i where n u stands for the normal velocity at the inlet of the model, C k are constants<br />

(such that Ck Ak<br />

iBk<br />

), 0 J and J 1 are Bessel functions of First Type order 0 and 1, k<br />

<br />

is the harmonic count in Fourier series, <br />

<br />

/ 2<br />

0<br />

k<br />

<br />

<br />

e<br />

<br />

<br />

<br />

i<br />

kt <br />

k R k<br />

is the Womersley index, is<br />

density, is the infinite-shear-rate viscosity, R is average radius of the inflow cross<br />

section, is the heart rate in radians per second (here, 2 rad/s) and x is the<br />

dimensionless distance from center of inflow.<br />

Patient 1 Patient 2 Patient 3 Patient 4<br />

Fig. 2 - The Views of Generated 3D CAD Models used For Unstented Analysis<br />

The Womersley index for the fundamental frequency is 3.2 for this study. The outlet<br />

boundary condition was time-varying pressure, given in the series-form<br />

kmax<br />

ikt<br />

Pout<br />

t P0<br />

Re <br />

Pk<br />

e as in [6]. No slip wall conditions were applied where the<br />

k 1<br />

<br />

blood met any solid structure – either the arterial wall or the stent wire. Carreau type<br />

nonlinear viscosity model was applied for the blood, parameters as in [7].<br />

Implicit time integration was applied with 200 steps per cardiac cycle (assumed to be<br />

1Hz). The meshing procedure was completed within HyperMesh Preprocessing<br />

Software (Altair Inc., USA) and then exported to AcuSolve for running. All meshes<br />

were tetrahedron elements with a finer resolution of the boundary layer. Each model<br />

solved on 48-core; 128GB RAM HP DL 585G7 servers on approximately 120hr of wall<br />

time per model with MPI parallelization. Transient velocity and pressure data for the<br />

whole model were transferred into EnSight Software for Post-Processing (CEI Inc). The<br />

data from the initial cardiac cycle was disregarded, and the remaining was used as to<br />

common practice in transient FE analysis to avoid appearing transients due to

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