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ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

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6. CONCLUSIONS<br />

The presented in the paper simulation system Cosmoprojector, in fact, is not only the<br />

mesh generator. The task – to simulate bone structural evolution – was divided into two<br />

elements to enable material consolidation and separation. First - structural evolution of<br />

the real tissue geometry by modifying the input information in the form of 2dimensional<br />

images corresponding to the way in medical imaging), and the second -<br />

mesh creation for the structural analysis purposes and determination of SED<br />

distribution. Due to parallelization of both: the structural as well as volume mesh<br />

generation, the presented remodeling simulation tool can be useful in analysis of whole<br />

bone elements. One of directions for future research will focus on analyzing the<br />

structure and interaction of implants with bone and trabecular bone remodeling around<br />

implants. Another one will focus on utilizing the observed optimization phenomenon in<br />

mechanical design, treating the pair bone-implant as a one system to design new type of<br />

implants according to biological principles. The initial concept of the presented<br />

simulation system was dedicated to the bone remodeling purposes. The principle of<br />

constant strain energy density on the structural surface has a perfect analogy in the<br />

structural optimization theory, so the presented system (with some modification) could<br />

be also useful .for pure mechanical optimization purposes. The unique feature of such<br />

approach is simultaneous size, shape and topology optimizations, something natural for<br />

biological entities, but completely new in the world of mechanical design [8].<br />

7. ACKNOWLEDGEMENTS<br />

The author would like to thank the PhD student Hubert Hausa, who performed the<br />

performance tests of the parallel mesh generation tool.<br />

8. REFERENCES<br />

1. Adachi, T., Tomita, Y., Functional Adaptation of Cancellous Bone in Human<br />

Proximal Femur Predicted by Trabecular Surface Remodeling Simulation toward<br />

Uniform Stress State, J Biomech, 2002, Vo. 35, 1541-1551.<br />

2. Huiskes, H.W.J. et al., Effects of mechanical forces on maintenance and adaptation<br />

of form in trabecular bone, Nature, 2000, Vol. 404, 704-706.<br />

3. Niebur, G.L., Feldstein, M.J., Yuen, J.C., Chen, T.J., Keaveny, T.M., High<br />

resolution finite element models with tissue strength asymmetry accurately predict<br />

failure of trabecular bone, J Biomech, 2000, Vol. 33, 1575-1583.<br />

4. Ruimerman, R. et al., A 3-dimensional computer model to simulate trabecular bone<br />

metabolism, Biorheology, 2003, Vol. 40, 315-320.<br />

5. Nowak, M., Structural optimisation system based on trabecular bone surface<br />

adaptation, Struct Multidiscip O, 2006, Vol. 32(3), 241-251.<br />

6. Nowak, M., A generic 3-dimensional system to mimic trabecular bone surface<br />

adaptation, Comput Method Biomec, 2006, Vol. 9(5), 313-317.<br />

7. Waarsing, J.H., Day, J.S. and Weinans H., An improved segmentation method for in<br />

vivo µCT Imaging, J. Bone Miner. Res., 2004, Vol. 19, 1640–1650.<br />

8. Nowak, M.,Improved aeroelastic design through structural optimization, 2011,<br />

Proceedings of the CMM-2011, 9-th Computer Methods in Mechanics Conference,<br />

http://cmm2011.il.pw.edu.pl/cd/pdf/074_f.pdf.

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