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ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

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(a) (b)<br />

Figure 9. Cumulative probability for the von Mises stress in the knee implants (a),<br />

contact pressure in UHMWPE.<br />

However, as outlined in this paper, a complex 3D model was generated and used in both<br />

stress and probabilistic analysis since the response surface method [11], by which a<br />

mathematical model is formed in place of a time consuming analysis, was utilized in<br />

order to carry out probabilistic analyses in a reasonable computational time.<br />

Having carried out probabilistic analysis, the cumulative probability curves for the von<br />

Mises stress distribution of the knee implant and the contact pressure on UHMWPE are<br />

given in Fig.9(a) and (b), respectively. As these results indicates, even for the stress<br />

values higher than the mean values of these stresses obtained from the deterministic<br />

analysis given in Fig.7, there is a great chance to occur. Therefore, any variation that the<br />

model might possible have during the design and analysis stages must be taken into<br />

account using a probabilistic analysis.<br />

6. CONCLUSIONS<br />

In this study, a realistic patient-specific model of the knee implant was developed to use<br />

in probabilistic analysis. The 3D model of the knee implant was obtained from a patient<br />

at the age of 65, suffering from gonarthrosis, and the 3D CAD model was modified by<br />

the orthopedic by slicing both femur and tibia.<br />

The knee implant model used in this paper includes a realistic separation of the cortical<br />

and trabecular bone without using a uniform thickness for the cortical along the femur<br />

and tibia. This model also has an empty medullary canal, rather than having trabecular<br />

bone in the most of the models in the literature.<br />

The material properties were assigned considering both the values in the literature and<br />

the HU values obtained from the patient’s CT data. Different grouping approaches were<br />

conducted to determine the distribution of the HU values of the trabecular bone, and<br />

statistical approaches were utilized to determine the distribution type with their<br />

parameters.<br />

After validation of the knee implant by comparing the results obtained with that in the<br />

literature, the probabilistic analysis was carried out in order to see the effect of the<br />

variations in the design parameters on the performance of the knee implant. As outlined<br />

in the results, the analysis presented in the paper illustrated that the probabilistic<br />

analysis helps to account for variations and uncertainties in knee implant design as<br />

opposed to the deterministic analysis.<br />

8

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