ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

6. CONCLUSION
In CFD simulations, the existence of both one and two AOs, compared to a single NO,
markedly increased the ventilation rate through maxillary sinuses. The flow rate through
a sinus with two AOs is comparable to a sinus with one AO, however, the presence of
two AOs complicates the flow partitioning of the gross maxillary sinus ventilation
among the ostia. Accessory ostia also may affect the direction of flow through the NO.
Whether these alterations have an impact on physiology or pathophysiology of the
sinuses remains unknown, and needs to be investigated by future human studies.
7. ACKNOWLEDGEMENT
The authors would like to acknowledge the support by a grant from the Swiss based
CMF Clinical Priority Program of the AO Foundation under the project number C-09-
2L as well as the Academic Research Grant (T208A3103) from the Ministry of
Education, Singapore. The research performed has been approved by the relevant
Institutional Review Board.
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