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ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

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Figure 2 Fragment of model and used FEM mesh<br />

The FE modelling was started by data collection. Thickness of the top skin layers was obtained for a 25 year old man by<br />

Optical Coherence Tomography (OCT). The OCT performs high-resolution, cross-section topographic imaging of the<br />

integral microstructure in tissue. Fig 3 shows an OCT image of human skin on the inner forearm of healthy 25 year old man.<br />

The OCT enables a measurement of the thickness of the outer layers such as epidermis and dermis. The different shades<br />

represent different layers of skin (see fig. 3) (see (Podoleanu, 2005) for full details). The white line on the top of skin it is not<br />

the stratum corneum, but a light reflection. The thickness of stratum corneum and deeper layers were obtained from literature<br />

(C.Pailler-Mattéi, 2006) (F. M. Hendriks, 2003) (Geerligs, 2009). The thickness of the layers is shown in Table 2.<br />

Figure 3 The OCT image of human skin on the inner forearm of healthy 25 years-old man.<br />

A tentative validation of the FE model was carried out by comparing indentation depth of the probe for the real test and<br />

the FE model. Unfortunately, Kwiatkowska et al. did not publish an indentation depth of the probe, but published a Young<br />

modulus for skin that was obtained during different test conditions. The indentation depth for the different loads and<br />

dimensions of the probe was calculated using Hertz theory. First the contact area was calculated between a smooth spherical<br />

steel indenter and the flat human skin. The contact radius a (Fig. 6.) as a function of the normal load F n radius of ball R and<br />

reduced modulus E*, can be described by equation 2 (Fischer-Cripps, 2002) (D.A. Spance, 1975) (C. Pailler-Mattéi, 2006).<br />

Figure 4 Contact between a sphere and an elastic half-space.<br />

where the equivalent elastic reduced modulus E* is given by the following expression (C. Pailler-Mattéi, 2006):<br />

(<br />

(<br />

For a rigid sphere in the contact with human skin the contribution of the elastic properties of the probe is negligible, so<br />

equation (3) can be reduced to (see (M. Kwiatkowska et al., 2009) for full details):<br />

)<br />

3<br />

)<br />

(2)<br />

(3)

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