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ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

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living [13, 14].<br />

Table 1. Load weight factors for the motions of abduction and anterior flexion.<br />

10º 30º 50º 70º 90º 110º<br />

Abduction 0.145735 0.069027 0.064054 0.031480 0.006265 0.001621<br />

Anterior flexion 0.312289 0.147916 0.137258 0.067456 0.013425 0.003474<br />

Starting from a uniform density distribution of 0.4, several values for the parameters κ<br />

and m are tested to reproduce the bone density of the scapula, which is taken from the<br />

CT scan images by relating the intensity of the image pixels with the bone apparent<br />

density [15]. The predictions from the bone remodeling model are evaluated by<br />

qualitative and quantitative comparisons. For the latter, the Pearson’s correlation<br />

coefficient r and the root-mean-square error (rms), based on a relative and an absolute<br />

difference, denoted as r<br />

and a<br />

, respectively, are computed. Mathematically, r<br />

and a<br />

are expressed as<br />

<br />

% <br />

i<br />

r<br />

<br />

i i<br />

BR CT<br />

i<br />

CT<br />

i i<br />

BR<br />

CT<br />

i<br />

g<br />

a <br />

cc<br />

<br />

<br />

(2)<br />

<br />

<br />

i<br />

i<br />

where BR and CT is the bone apparent density taken from the bone remodeling<br />

simulation and the CT scan images for node i, respectively.<br />

4. RESULTS<br />

4<br />

4<br />

Bone remodeling simulations are performed considering values of 1<br />

10 , 2 10 ,<br />

4<br />

4<br />

4<br />

4<br />

4<br />

4<br />

4<br />

3<br />

3<br />

3<br />

10 , 4 10 , 5<br />

10 , 6 10 , 7 10 , 8 10 , 9 10 , 1<br />

10 , 1.<br />

2 10 and<br />

3<br />

1.<br />

4 10 for the parameter κ and 1, 2, 3, 4, 5, 6, 7 and 8 for the parameter m. Given that<br />

the rms of the absolute and relative differences point towards different best solutions, an<br />

average error is considered instead by taking into account both criteria. It is important to<br />

note that the rms of each criterion is normalized by its maximum so that the contribution<br />

to the average error is dimensionless and, at most, unitary. Figures 2a and 2b present the<br />

average errors and the Pearson’s coefficients for the performed simulations,<br />

respectively. The results present the solutions with parameter m of 4 and 5 as the most<br />

suitable. Furthermore, if the mean bone density of the whole scapula and its standard<br />

4<br />

deviation is analyzed, the solution with parameter κ of 4 10 appears to stand out as it<br />

compares well with the actual mean bone density and standard deviation. In particular,<br />

the analyzed scapula presents a mean bone density and standard deviation of 1.01 and<br />

0.39 g/cc, while this solution presents 1.01 and 0.33 g/cc, respectively. Also, regarding<br />

the absolute difference, the rms is only 0.379 g/cc and almost 70% and 90% of the<br />

nodes present an absolute error lower than 0.4 and 0.6 g/cc, respectively. Based on the<br />

4<br />

above reasoning, the solution with parameter κ of 4 10 and parameter m of 5 appears<br />

to be the most suitable to reproduce the bone density distribution of the specimen’s<br />

scapula. The visual comparison between the predicted bone densities and the CT scan<br />

images show, in general, a rather good similarity.<br />

5. DISCUSSION<br />

Finite element analysis can provide an important insight into the long-term effects of the<br />

glenoid prostheses on the bone adaptation process and thus enable a continuous

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