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ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

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4. RESULTS<br />

The results of the algorithmic procedure as shown in Fig. 6 proved to be suitable for<br />

biomechanical finite element (FE) analysis. Exemplary simulations using the<br />

contemporary FE codes KASKADE, developed at ZIB Berlin, Germany, [7] or ANSYS<br />

[8] can be found in [9-12].<br />

Notably, refined FE simulations following the proposed concept have already produced<br />

significant results proving a relevant influence of tissue anisotropy on the mandibular<br />

biomechanics. A comparison of the load distributions in isotropic and anisotropic<br />

simulations indicates that a maximum degree of anisotropy leads to kind of load<br />

minimization of the mandible, expressed by a minimum of different norms of local<br />

volumetric strain, evaluated throughout the organ. So, it seems that tissue anisotropy is<br />

not only qualitatively relevant for the mandibular structural behaviour, but that in some<br />

sense, “the anisotropy spares the mandible from loading” [9, 10, 12].<br />

a b<br />

Figure 6. Result of the algorithmic procedure, mandible with circumferential (a) and<br />

axial (b) anisotropic trajectories, dorsal view of a mandible with trajectories in all three<br />

directions (c), visualization technique for a and b: illuminated stream lines [13].<br />

5. ACKNOWLEDGEMENT<br />

This work was supported under the Theme FP7-2008-SME-1 of the 7 th Framework<br />

Programme of the European Commission, Grant no. 232164, BIO-CT-EXPLOIT.<br />

c

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