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ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

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considered. It has been proposed on the market to overcome the drawbacks of culotte<br />

technique, which is one of the most commonly applied double-stenting procedures [2].<br />

This technique consists of the implantation of a device in the SB of the bifurcation, the<br />

re-wiring, the treatment of the main branch (MB) through the struts of the previously<br />

implanted stent and, finally, the final kissing balloon inflation (FKB, simultaneous<br />

expansion of two balloons in both branches of the bifurcation). Main advantages of the<br />

culotte technique are the good coverage of the whole bifurcation and the suitability for<br />

all the bifurcation angles. However, this method provokes a high concentration of metal<br />

in the proximal part of the MB due to the overlap of the devices that could lead to instent<br />

restenosis and thrombosis. The particular design of the Tryton stent, characterized<br />

by few struts in its proximal part, should allow a decrease of the overlap region and also<br />

an easy access to the implantation site for the second device.<br />

The aim of this work is the numerical analysis of the culotte technique both from a<br />

structural and fluid dynamic point of view, in order to compare the behavior of the<br />

Tryton stent with a standard one. In particular, the performance of the dedicated stent is<br />

evaluated in terms of ease of use during the treatment and biomechanical influence after<br />

stents implantation. From the structural point of view, stress fields obtained in the<br />

device and in the arterial wall and the metal-to-artery ratio are analyzed. From the fluid<br />

dynamic point of view near-wall quantities like wall shear stress (WSS) are evaluated.<br />

3. MATERIALS AND METHODS<br />

3.1 Structural model<br />

An ideal coronary bifurcation model (Fig. 1b) is created with realistic geometrical<br />

dimensions and a bifurcation angle of 45° using Rhinoceros 4.0 Evaluation CAD<br />

program (McNeel & Associates, Indianapolis, IN, USA). An isotropic hyperelastic<br />

behavior is assigned to the three different layers composing the arterial wall,<br />

considering the experimental data obtained by Holzapfel [3].<br />

Stent geometries (Fig. 1a) are obtained using the previously mentioned CAD software<br />

and resemble the Tryton and the Multilink Vision (Abbott Laboratories. Abbott Park,<br />

Illinois, U.S.A) stents. The material, a cobalt-chromium alloy, is described through a<br />

Von Mises-Hill plasticity model with isotropic hardening.<br />

In order to simulate the stenting procedures, cylindrical polymeric balloons are created<br />

in the expanded shape and then deflated by applying a negative pressure to the internal<br />

surface, obtaining a multi-folded geometry (Fig. 1c). The balloons are modeled as an<br />

elastic membrane. Bended configurations of the balloons are needed to reproduce some<br />

steps of the procedure like the FKB. To achieve these configurations, preliminary<br />

simulations are carried out where a deflated balloon slides along a specifically drawn<br />

guide (Fig. 1c).<br />

Numerical simulations of stents deployment are performed using the ABAQUS/Explicit<br />

commercial code (Dassault Systemes Simulia Corp., RI, USA) assuming the condition<br />

of quasi-staticity of the phenomenon [4]. Contacts between parts of the model are<br />

defined according to general contact algorithm.<br />

Two different simulations of the culotte technique are carried out. In the first analysis<br />

(Fig. 2A) a Tryton stent is expanded as a SB device with a Multilink Vision stent<br />

implanted in the MB as a workhorse stent. In the second analysis, the bifurcation is<br />

treated with two standard Multilink Vision devices in either the SB and the MB (Fig.<br />

2B). The whole technique can be summarized through the following steps: i) stenting of

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