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ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

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Figure 5. Comparison of the access to MB after SB stenting: A) Multilink Vision; B)Tryton; C) Tryton<br />

rotated of 30°; D) Tryton rotated of 60°. The green region represents the area available for an optimal<br />

re-crossing.<br />

access to MB providing a higher area suitable to obtain an optimal final configuration.<br />

This work indicates that new dedicates approaches could contribute to improve the<br />

biomechanical influence of the current treatment of coronary bifurcations.<br />

6. REFERENCES<br />

1. Collet, C., Costa R.A. and Abizaid A., Dedicated bifurcation analysis: dedicated<br />

devices, Int. J. Cardiovasc. Imaging, 2011, Vol. 27(2), 181-188.<br />

2. Latib, A. and Colombo A., Bifurcation disease: what do we know, what should we<br />

do?, J. Am. Coll. Cardiol. Intv., Vol. 1(3), 218-226.<br />

3. Holzapfel, G.A., Sommer, G., Gasser, C.T. and Regitnig, P., Determination of layerspecific<br />

mechanical properties of human coronary arteries with non-atherosclerotic<br />

intimal thickening and related constitutive modelling”, Am. J. Physiol. Heart. Circ.<br />

Physiol., 2005, Vol. 289, H2048–H2058.<br />

4. Gastaldi, D., Morlacchi, S., Nichetti, S., Capelli, C., Dubini, G., Petrini, L. and<br />

Migliavacca, F., Modelling of the provisional side-branch stenting approach for the<br />

treatment of atherosclerotic coronary bifurcations: effects of stent positioning,<br />

Biomech. Model. Mechanobiol., 2010, Vol. 9, 551-561.<br />

5. Morlacchi, S., Chiastra, C., Gastaldi, D., Pennati, G., Dubini, G. and Migliavacca,<br />

F., Sequential structural and fluid dynamic numerical simulations of a stented<br />

bifurcated coronary artery, J. Biomech. Eng., 2011, Vol. 133, 121010.<br />

6. Chiastra, C., Morlacchi, S., Pereira, S., Dubini, G. and Migliavacca, F.,<br />

Computational fluid dynamics of stented coronary bifurcations studied with a hybrid<br />

discretization method, Eur. J. Mech. B-Fluid. In press.<br />

7. Seo, T., Schachter, L.G. and Barakat, A.I., Computational study of fluid mechanical<br />

disturbance induced by endovascular stents, Ann. Biomed. Eng., 2005, Vol. 33(4),<br />

444-456.<br />

8. Davies, J.E., Whinnett, Z.I., Francis, D.P., Manisty, C.H., Aguado-Sierra, J.,<br />

Willson, K., Foale, R.A., Malik, I.S., Hughes, A.D., Parker, K.H. and Mayer, J.,<br />

Evidence of dominant backward-propagating “suction” wave responsible for<br />

diastolic coronary filling in humans, attenuated in left ventricular hypertrophy,<br />

Circulation, 2006, Vol. 113, 1768-1778.<br />

9. Guerin, P., Pilet, P., Finet, G., Goueffic, Y., N’Guyen, J.M., Crochet, D., Tijou, I.,<br />

Pacaud, P. and Loirand, G., Drug-Eluting stents in bifurcations bench study of strut<br />

deformation and coating lesions, Circ. Cardiovasc. Intv., 2010, Vol. 3, 120-126.<br />

10. Himburg, H.A., Grzybowski, D.M., Hazel, A.L., LaMack, J.A., Li, X.M. and<br />

Friedman, M.H., Spatial comparison between wall shear stress measures and porcine<br />

arterial endothelial permeability. Am. J. Physiol. Heart Circ. Physiol., 2004, Vol.<br />

286, H1916-H1922.

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