ARUP; ISBN: 978-0-9562121-5-3 - CMBBE 2012 - Cardiff University

Figure6 . The stroke volume data for Doppler-Echo( green), Aorta with drop( red), and
Aorta without pressure drop(Blue)
5. DISCUSSION
Most of available previous research has calculated cardiac output and stroke volume
using statistical methods but we have used a numerical method and compared the results
to a subject. Korakianitis [ 1] used Wind-Kassel model to calculate cardiac output in
rest condition for both normal and abnormal conditions.
He calculated the value of 7500
ml/min in rest. However Podnar [ 2]
calculated cardiac output value as 5000 ml/min in
rest but maximum 5500 ml/min in heart beat of 120. Our results have a good agreement
with clinical data of Christie et al [ 3] who introduced an ascending curve for cardiac
output.
We are currently working on 3D model of aortic valve to calculate the cardiac output
and stroke volume. One of limitation of the model is that maximum opening of aortic
valve is constant during exercise.
6. COCLUSION
We introduced a numerical model for calculation of cardiac output and stroke volume
during the rest and exercise condition using a flexible aortic valve. The results were
compared to Doppler-Echocardiographic results from one subject.
7. REFERENCES
1. Shi, T. Korakianitis and Y. Numerical simulation of cardiovascular dynamics with
healthy and diseased heart valves. s.l. , Journal of Biomechanics, Vol 3, pp. 1964–
1982, 2006.
2. Podnar, T.; Runovc, F.; Milisav, I. & Kordaš, M. Simulation of some short- term
control mechanisms in cardiovascular physiology. Computers in Biology and Medicine
Vol.34, pp. 35-49,
ISSN 0010-4825,
2004.