Review of Pharmacology - 9E (2015)

Autonomic Nervous System
88
Review of Pharmacology
(c) β 2
blocker
(d) Antioxidant
(e) Used in hypertension
183. True about esmolol is: (PGI June, 2003)
(a) It is an α-blocker
(b) It has no intrinsic sympathomimetic activity
(c) It has a long half life
(d) It is a cardioselective β-blocker
(e) It can precipitate heart failure
184. True about esmolol is: (PGI June, 2003)
(a) It is a cardioselective β-blocker
(b) It increases airway resistance
(c) It causes tachycardia
(d) Its t ½ is 4 hrs
(e) It has negative inotropic activity (PGI Dec. 2002)
185. β-blockers with intrinsic sympathomimetic properties
are: (PGI Dec. 2002)
(a) Propanolol
(b) Oxprenolol
(c) Pindolol
(d) Esmolol
(e) Butoxamine
186. Properties making cardioselective beta-blockers
desirable are: (PGI June, 2002)
(a) Less bronchoconstriction
(b) Less adverse effect on lipid profile
(c) Less likely to cause glucose intolerance
(d) May be used in Raynaud’s disease
(e) Less liable to impair exercise capacity
187. The property which makes betaxolol different from
timolol is that betaxolol:
(a) Is a β 1
selective blocker
(b) Is more efficacious in glaucoma
(c) Produces less ocular side effects
(d) Is shorter acting
188. A drug ‘X’ is an α adrenergic blocker but paradoxically
produces vasoconstriction. ‘X’ is:
(a) Phenoxybenzamine
(b) Ergotamine
(c) Prazosin
(d) Tolazoline
189. An old man Baba comes to you and is diagnosed to be
having benign hypertrophy of prostate. The drug which
provides faster and greater symptomatic relief to this
patient will be:
(a) Terazosin
(b) Desmopressin
(c) Finasteride
(d) Sildenafil
190. Beta adrenergic blocker having cardioselectivity,
intrinsic sympathomimetic activity and membrane
stabilizing property is:
(a) Carvedilol
(b) Atenolol
(c) Acebutolol
(d) Metoprolol
191. Propanolol, a non-selective beta blocker can be
prescribed to decrease anxiety associated with:
(a) Chronic neurotic disorder
(b) Schizophrenia
(c) Short term stressful situations
(d) Endogenous depression
192. All of the following are features of metoprolol in
comparison to propanolol except:
(a) It is ineffective in suppressing muscle tremor
(b) It is safer in diabetics
(c) It is less likely to cause bradycardia
(d) It is less likely to worsen Raynaud’s disease
193. Which of the following effects of adrenaline would be
blocked by phentolamine but not by propanolol?
(a) Cardiac stimulation
(b) Relaxation of bronchial smooth muscle
(c) Relaxation of the uterus
(d) Contraction of the radial smooth muscle in the iris
194. Propanolol is useful in the treatment of all of the
following except:
(a) Angina
(b) Partial atrioventricular block
(c) Idiopathic hypertrophic subaortic cardiomyopathy
(d) Familial tremor
195. Adverse effects that limit the use of adrenoceptor
blockers include:
(a) Bronchoconstriction from α blocking agents
(b) Heart failure exacerbation from β blockers
(c) Impaired blood sugar response with α blockers
(d) Increased intraocular pressure with β blockers
196. An old patient Ram Kishore having asthma and
glaucoma is to receive a β blocker. Regarding β blocking
drugs: (Karnataka 2005)
(a) Metoprolol blocks β 2
receptors selectively
(b) Esmolol’s pharmacokinetics are compatible with
chronic topical use
(c) Nadolol lacks β 2
blocking action
(d) Timolol lacks the local anaesthetic effects of propanolol
197. Which of the following drug is a third generation
β-blocker?
(a) Propanolol
(b) Timolol
(c) Nadolol
(d) Nebivolol
198. In a patient Kishore having hypertension, propanolol
was given. Though the drug controlled hypertension
but it reduced resting heart rate to 50/min. Which of
the following β blockers can be used in this patient
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