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Review of Pharmacology - 9E (2015)

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<strong>Review</strong> <strong>of</strong> <strong>Pharmacology</strong><br />

Autonomic Nervous System<br />

92<br />

31. Atropine is added to commercial preparations containing<br />

diphenoxylate to:<br />

(a) Potentiate us anti-spasmodic effect<br />

(b) To reduce excretion <strong>of</strong> salt and water<br />

(c) To prevent overdosage and discourage opioid dependence<br />

(d) To prolong its duration <strong>of</strong> action<br />

32. Beta-adrenoceptor blocking agent that should be<br />

avoided in patients with renal failure is:<br />

(a) Atenolol<br />

(b) Metoprolol<br />

(c) Propranolol<br />

(d) Esmolol<br />

33. The mydriatic drug with short duration <strong>of</strong> action is:<br />

(a) Cyclopentolate<br />

(b) Tropicamide<br />

(c) Homatropine<br />

(d) Atropine<br />

34. All <strong>of</strong> the following are used in organophosphorus<br />

poisoning except:<br />

(a) Pralidoxime<br />

(b) Atropine<br />

(c) Activated charcoal<br />

(d) Naltrexone<br />

35. A 35 year old man was found unconscious. Examination<br />

revealed bilateral constricted pupils, bradycardia,<br />

excessive sweating and secretion. Most likely cause is:<br />

(a) Opium poisoning<br />

(b) Acute alcohol intoxication<br />

(c) Organophosphorous poisoning<br />

(d) Pontine hemorrhage<br />

36. Which one <strong>of</strong> the following drugs does not induce mydriasis:<br />

(a) Phentolamine<br />

(b) Ephedrine<br />

(c) Phenylephrine<br />

(d) Cocaine<br />

37. Blockade <strong>of</strong> neuromuscular transmission by botulinum<br />

toxin is an example <strong>of</strong>:<br />

(a) Depolarizing blockade<br />

(b) Competitive blockade<br />

(c) Presynaptic blockade<br />

(d) Postsynaptic blockade<br />

38. Atropine when used as a pre-medication causes all <strong>of</strong><br />

the following symptoms except:<br />

(a) Skin flush<br />

(b) Bronchoconstriction<br />

(c) Prevents bradycardia<br />

(d) Dryness <strong>of</strong> mouth<br />

39. Patients taking a b-adrenergic receptor blocking drug<br />

may experience all <strong>of</strong> the following except:<br />

(a) Exacerbation <strong>of</strong> existing heart block<br />

(b) Precipitation <strong>of</strong> heart failure<br />

(c) Nasal blockage<br />

(d) Cold extremities<br />

40. Beta blocker with peripheral vasodilator action is:<br />

(a) Propanolol<br />

(b) Carvedilol<br />

(c) Atenolol<br />

(d) Acebutolol<br />

41. Which <strong>of</strong> the following drugs is useful in anaphylactic<br />

shock:<br />

(a) Isoprenaline<br />

(b) Adrenaline<br />

(c) Non-adrenaline<br />

(d) Terbutaline<br />

42. A 24 years old farm worker is rushed to a nearby emergency<br />

department after an accidental exposure to parathion.<br />

Which <strong>of</strong> the following drugs can be given to<br />

increase the activity <strong>of</strong> his acetyl cholinesterase:<br />

(a) Atropine<br />

(b) Dimercaprol<br />

(c) Physostigmine<br />

(d) Pralidoxime<br />

43. Which <strong>of</strong> the following drug is not used in treatment <strong>of</strong><br />

iridocyclitis:<br />

(a) Atropine eye ointment<br />

(b) Pilocarpine eye drops<br />

(c) Timolol eye drops<br />

(d) Steroid eye drops<br />

44. All <strong>of</strong> the following are the feature <strong>of</strong> atropine poisoning<br />

except:<br />

(a) Mydriasis<br />

(b) Hallucinations<br />

(c) Hypothermia<br />

(d) Coma<br />

45. Catecholamines are synthesized from:<br />

(a) Alanine<br />

(b) Glycine<br />

(c) Cysteine<br />

(d) Tyrosine<br />

46. The drug that is contraindicated in angle closure glaucoma<br />

is:<br />

(a) Pilocarpine<br />

(b) Atropine<br />

(c) Dorzolamide<br />

(d) Timolol<br />

47. Pilocarpine reduce the intraocular pressure in persons<br />

with closed angle glaucoma by:<br />

(a) Reducing aqueous humor secretion<br />

(b) Contrating iris sphincter muscle<br />

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