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Review of Pharmacology - 9E (2015)

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<strong>Review</strong> <strong>of</strong> <strong>Pharmacology</strong><br />

Cardiovascular System<br />

(c) Propanolol<br />

(d) Reserpine<br />

99. A pregnant patient, Lata is admitted for the workup <strong>of</strong><br />

hemolytic anemia. She is giving the history <strong>of</strong> taking<br />

an antihypertensive drug after beginning <strong>of</strong> her pregnancy.<br />

The most likely cause would be:<br />

(a) Minoxidil<br />

(b) Clonidine<br />

(c) Methyl dopa<br />

(d) Labetalol<br />

100. A patient Shyam is admitted to the emergency following<br />

a drug overdosage with severe tachycardia. He had been<br />

receiving therapy for hypertension and angina. Which<br />

<strong>of</strong> the following drugs can cause tachycardia?<br />

(a) Guanethidine<br />

(b) Isosorbide dinitrate<br />

(c) Propanolol<br />

(d) Verapamil<br />

101. Devesh is working as a CEO in a company. He has a<br />

traveling job. He is a known diabetic controlled on oral<br />

hypoglycemic drugs. On his recent visit to the doctor,<br />

his blood pressure was found to be 164/102 mm Hg.<br />

Most suitable drug for this patient should be?<br />

(a) Propanolol<br />

(b) Enalapril<br />

(c) Clonidine<br />

(d) Hydrochlorthiazide<br />

102. A 40-year-old politician suffered from attacks <strong>of</strong> chest<br />

pain diagnosed as angina pectoris. He had a tense<br />

personality, resting heart rate was 96/min blood pressure<br />

170/104mm Hg, but blood sugar level and lipid pr<strong>of</strong>ile<br />

were normal. Select the most suitable antihypertensive<br />

for the initial therapy in his case:<br />

(a) Nifedipine<br />

(b) Hydrochlorothiazide<br />

(c) Atenolol<br />

(d) Methyldopa<br />

103. Rajat jain was presented to casuality in an unconscious<br />

state. His blood pressure was found to be 220/110 mm<br />

Hg. Most suitable drug for this patient to rapidly decrease<br />

the blood pressure is:<br />

(a) Sublingual nifedipine<br />

(b) Intramuscular injection <strong>of</strong> hydralazine<br />

(c) Intravenous infusion <strong>of</strong> sodium nitroprusside<br />

(d) Intravenous injection <strong>of</strong> clonidine<br />

104. Which <strong>of</strong> the following antihypertensive drug does not<br />

alter serum glucose and lipid levels?<br />

(a) Propanolol (MH 2006)<br />

(b) Prazosin<br />

(c) Thiazide diuretics<br />

(d) None <strong>of</strong> the above<br />

105. Drug not useful in hypertensive emergency is:<br />

(a) IV hydralazine (DPG 2005)<br />

(b) Indapamide<br />

(c) Sublingual nifedipine<br />

(d) Sodium nitroprusside<br />

106. Which <strong>of</strong> the following is not an adrenergic neuron<br />

blocking drug? (DPG 2000)<br />

(a) Reserpine<br />

(b) Guanethidine<br />

(c) Bretylium<br />

(d) Minoxidil<br />

107. Which <strong>of</strong> the following drug has a favourable effect on<br />

lipid metabolism? (MPPG 2006)<br />

(a) Atenolol<br />

(b) Chlorothiazide<br />

(c) Clonidine<br />

(d) Torsemide<br />

108. The choice <strong>of</strong> antihypertensive medication also depends<br />

upon the co-morbid illness <strong>of</strong> the patient and all <strong>of</strong> the<br />

following recommendations have been made EXCEPT:<br />

(MPPG 2006)<br />

(a) In hypertensive patients with heart failure, ACE<br />

inhibitors may be preferred<br />

(b) In hypertensive patients with migraine, beta blockers<br />

are an excellent choice<br />

(c) In hypertensive patients with gout, diuretics are<br />

particularly useful<br />

(d) In hypertensive patients with peripheral vascular<br />

disease, calcium channel blockers are recommended.<br />

109. An anti-hypertensive drug that causes positive Coomb’s<br />

test is: (UP 2008)<br />

(a) Methyldopa<br />

(b) Clonidine<br />

(c) Hydralazine<br />

(d) Sodium-nitropruside<br />

110. The drug <strong>of</strong> choice in digitalis induced ventricular<br />

arrhythmias is: (UP 2006)<br />

(a) I.V. Lignocaine<br />

(b) Phenytoin<br />

(c) Quinidine<br />

(d) Procainamide<br />

111. Drug <strong>of</strong> choice in pregnancy induced hypertension is<br />

(a) Amoldipine (MH 2003, RJ 2009)<br />

(b) Losartan<br />

(c) Diuretic<br />

(d) Methyldopa<br />

112. Centrally acting sympatholytic agent used as antihypertensive<br />

agent is: (MH 2006)<br />

(a) Propanolol<br />

(b) Clonidine<br />

(c) Prazosin<br />

(d) Phenoxybenzamine<br />

182<br />

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