Review of Pharmacology - 9E (2015)

Central Nervous System
352
Review of Pharmacology
162. Buspirone is used as a/an: (AIIMS Nov 2009)
(a) Anxiolytic
(b) Sedative
(c) Muscle relaxant
(d) Anticonvulsant
163. All are indications of lithium except: (AI 2009)
(a) Neutropenia
(b) Major Depression
(c) Vasculogenic Headache
(d) Generalized anxiety disorder
164. All of the following drugs are atypical antipsychotics
except? (AIIMS May 2008)
(a) Olanzapine
(b) Clozapine
(c) Risperidone
(d) Thioridazine
165. Increased suicidal tendency is associated with alteration
in the brain levels of: (AIIMS May 2008)
(a) Noradrenaline
(b) Serotonin
(c) Dopamine
(d) GABA
166. All of the following drugs can cause neuroleptic
malignant syndrome except: (AIIMS Nov 2008)
(a) Amantadine
(b) Domperidone
(c) Haloperidol
(d) Metoclopramide
167. Correct about the use of lithium as an important
component of management of manic-depressive psycho
sis is: (DPG 2009)
(a) Is associated with delayed (>2 weeks) electrolyte disturbances
(b) Can be given alone for acute episodes
(c) Monitoring of serum concentration is seldom useful
for guiding dose adjustment
(d) Cause benign and reversible depression of T wave
on ECG
168. In depression, there is deficiency of: (DPG 2009)
(a) 5-HT
(b) Acetylcholine
(c) Dopamine
(d) GABA
169. Nocturnal enuresis is commonly treated with:
(a) Imipramine (DPG 2009)
(b) Chlordiazepoxide
(c) Haloperidol
(d) Chlorpromazine
170. Lithium is used in the prophylactic treatment of:
(a) Schizophrenia (DPG 2009)
(b) MDP
(c) Acute depression
(d) Conversion reaction
171. Risperidone is most commonly used to treat which of
the following disorders? (DPG 2009)
(a) Dementia
(b) Depression
(c) Schizophrenia
(d) Obsessive-compulsive disorder
172. As a side effect the metabolic syndrome is most commonly
associated with which of the following group of
medications? (DPG 2009)
(a) Anti-anxiety drugs
(b) Anti-depressant drugs
(c) Anti-psychotic drugs
(d) Anti-cholinergic drugs
173. Which of the following is the most common side effect
seen with fluoxetine therapy? (AI 2006)
(a) Seizure
(b) Anxiety
(c) Hypotension
(d) Loose stools
174. All are side effects of clozapine EXCEPT: (AI 2006)
(a) Granulocytopenia
(b) Seizures
(c) Sedation
(d) Extrapyramidal side effects
175. Antipsychotic drug induced Parkinsonism is treated
by: (AI 2005)
(a) Anticholinergics
(b) Levodopa
(c) Selegiline
(d) Amantadine
176. Oculogyric crisis is known to be produced by all of the
following drugs EXCEPT: (AI 2005)
(a) Trifluperazine
(b) Atropine
(c) Prochlorperazine
(d) Perphenazine
177. Mechanism of action of tianeptin in the brain is:
(a) Selective serotonin reuptake inhibition (AI 2002)
(b) Selective serotonin reuptake enhancement
(c) Selective dopamine reuptake inhibition
(d) Selective norepinephrine reuptake inhibition
178. False statement about selegiline is: (AI 2001)
(a) It is a MAO-A inhibitor
(b) Does not cause cheese reaction
(c) It decreases wearing off effect of levo-dopa
(d) It is used in Parkinsonism
179. The following statements are true for the therapy with
lithium EXCEPT: (AIIMS May, 2004)
(a) It is used in bipolar disorder
(b) Amiloride is useful in treating lithium induced diabetes
insipidus
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