Review of Pharmacology - 9E (2015)

Review of Pharmacology
Immunomodulators
5. Basiliximab acts by antagonism against:
(a) CD 25
(b) CD 11a
(c) TNF
(d) IL-2
6. Bevacizumab is:
(a) Monoclonal antibody against VEGF
(b) Anti-IL-2 monoclonal antibody
(c) Monoclonal antibody against FGFR
(d) Monoclonal antibody against EGFR
7. Rituximab is antibody against:
(a) CD 20
(b) VEGF
(c) EGER
(d) IL-2
8. True about azathioprine is:
(a) It has more anti tumor effect than immunosuppressant
effect
(b) It is not a prodrug
(c) It selectively affects differentiation of T cells
(d) It is a pyrimidine antimetabolite
9. Thalidomide is not used in:
(a) HIV related neuropathy
(b) Erythema nodosum leprosum
(c) HIV related oral ulcer
(d) Behcet’s disease
10. All of the following are tumor necrosis factor blocking
agents, except:
(a) Adalimumab
(b) Eternacept
(c) Infliximab
(d) Abciximab
11. Which of the following immunosuppressive agent requires
monitoring of renal function on regular basis?
(a) Azathioprine
(b) Mycophenolate mofetil
(c) Methotrexate
(d) Cyclosporine A
12. A topical retinoid recently introduced for the treatment
of psoriasis is:
(a) Adapalene
(b) Tazarotene
(c) Alitretinoin
(d) Bexarotine
13. Immunostimulant agent among the following is:
(a) Pirenzepine
(b) Levamisol
(c) Albendazole
(d) Methotrexate
14. Antihelminthic also acting as immunomodulator is:
(a) Albendazole
(b) Levamisole
(c) Mebendazole
(d) Piperazine
15. Cyclosporin-A acts on:
(a) CD4 cells
(b) CD3 cells
(c) CD8 cells
(d) B lymphocytes
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