Review of Pharmacology - 9E (2015)

Endocrinology
270
Review of Pharmacology
(c) Does not produce an active metabolite
(d) Does not inhibit peripheral conversion of T 4
to T 3
30. Fastest acting anti-thyroid drug is:
(a) Lugol’s iodine
(b) Radioactive iodine
(c) Propylthiouracil
(d) Sodium thiocyanate
31. The physical half life of radioactive I 131 is:
(a) 8 hrs
(b) 8 days
(c) 16 days
(d) 60 days
32. Beta blockers are used in hyperthyroidism:
(a) As short term symptomatic therapy till effect of
carbimazole develops
(b) As long term therapy after subtotal thyroidectomy
(c) In patient not responding to carbimazole
(d) To potentiate the effect of radioactive iodine
33. I 131 is the preferred treatment for:
(a) Children
(b) Young adults with recent onset Graves’ disease
(c) Elderly patients with ischemic heart disease
(d) Pregnant women
34. In the treatment of hypothyroidism, thyroxine is
preferred over liothyronine because thyroxine:
(a) Is faster acting
(b) Has higher affinity for thyroid hormone receptors
(c) Has a longer half life
(d) Can be made more easily by recombinant DNA
technology
35. A pregnant female Salma with thyrotoxicosis is
planned for surgery. Before surgery can be done, her
gland should be reduced in size and vascularity by
administering:
(a) Iodide ion
(b) Propanolol
(c) Propylthiouracil
(d) Radioactive iodine
36. Manish, a patient of hypothyroidism was prescribed
lthyroxine. Which of the following is the most reliable
guide for adjustment of thyroxine dose in him?
(a) Pulse rate
(b) Body weight
(c) Serum thyroxine level
(d) Serum TSH level
37. Which of the following is not used in the management
of thyroid storm? (DPG 2010)
(a) Potassium iodide
(b) Reserpine
(c) Propanolol
(d) Calcium channel blockers
38. Plasma half life of carbimazole is: (DPG 2006)
(a) 4 hours
(b) 8 hours
(c) 16 hours
(d) 24 hours
39. All are antithyroid drugs except: (UP 2006)
(a) Propylthiouracil
(b) Methimazole
(c) Carbimazole
(d) Carbamazepine
40. L-Thyroxine is used in: (UP 2006)
(a) Thyroid storm
(b) Cretinism
(c) Endemic goiter
(d) Grave’s disease
41. Safest treatment of hyperthyroidism in pregnant
women is: (Karnataka 2004, SGPGI 2002, MH 2002)
(a) Radioactive iodine
(b) Methimazole
(c) Carbimazole
(d) Propylthiouracil
42. All are causing hypothyroidism except: (Bihar 2005)
(a) PAS
(b) Captopril
(c) Lithium
(d) Amiodarone
43. Conversion of T 4
to T 3
inhibition is associated with:
(a) Propylthiouracil (AP 2001)
(b) Ampicillin
(c) Lithium
(d) Carbimazole
pancreas and diabetes mellitus
44. Which of the following anti-diabetic drugs can cause
vitamin B 12
deficiency? (AI 2012)
(a) Glipizide
(b) Acarbose
(c) Metformin
(d) Pioglitazone
45. Which of the following drugs does not cause hy po -
glycemia: (AIIMS May 2011)
(a) Acarbose
(b) Insulin
(c) Glimepride
(d) Nateglinide
46. A patient is receiving insulin and acarbose for diabetes
mellitus and developed hypoglycemia. Which of the
following should be used for treatment of hypoglycemia
in this patient? (AIIMS May 2011)
(a) Sucrose
(b) Galactose
https://kat.cr/user/Blink99/