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Review of Pharmacology - 9E (2015)

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103. Which <strong>of</strong> the following drugs are believed to be effective<br />

in the treatment <strong>of</strong> post operative shivering?<br />

(a) Ondansetron (DPG 2009)<br />

(b) Dicl<strong>of</strong>enac sodium<br />

(c) Pethidine<br />

(d) Paracetamol<br />

104. “MAC” <strong>of</strong> desflurane is: (DPG 2009)<br />

(a) 1.15<br />

(b) 2<br />

(c) 4<br />

(d) 6<br />

105. Which <strong>of</strong> the following should be considered as the cause<br />

<strong>of</strong> generalized convulsions 20 minutes postoperatively?<br />

(DPG 2009)<br />

(a) Halothane<br />

(b) Enflurane<br />

(c) Is<strong>of</strong>lurane<br />

(d) Sev<strong>of</strong>lurane<br />

106. Remifentanil is: (PGI Dec. 2007)<br />

(a) Long acting anaesthetic<br />

(b) Useful for short painful procedures<br />

(c) Administered by intravenous bolus dose<br />

(d) Metabolized by plasma esterases<br />

(e) Equipotent as fentanyl<br />

107. The minimal alveolar concentration <strong>of</strong> an inhalational<br />

anaesthetic is a measure <strong>of</strong> its:<br />

(a) Potency<br />

(b) Therapeutic index<br />

(c) Diffusibility<br />

(d) Oil: water partition coefficient<br />

108. Which general anaesthetic selectively inhibits excitatory<br />

NMDA receptors:<br />

(a) Thiopentone<br />

(b) Halothane<br />

(c) Desflurane<br />

(d) Ketamine<br />

109. ‘Second gas effect’ is exerted by which <strong>of</strong> the following<br />

gas when coadministered with halothane:<br />

(a) Nitrous oxide<br />

(b) Cyclopropane<br />

(c) Nitrogen<br />

(d) Helium<br />

110. Which <strong>of</strong> the following general anaesthetics has poor<br />

muscle relaxant action?<br />

(a) Ether<br />

(b) Nitrous oxide<br />

(c) Halothane<br />

(d) Is<strong>of</strong>lurane<br />

111. Select the correct statement about nitrous oxide:<br />

(a) It irritates the respiratory mucosa<br />

(b) It has poor analgesic action<br />

(c) It is primarily used as a carrier and adjuvant to other<br />

anaesthetics<br />

Anaesthesia<br />

(d) It frequently induces post anaesthetic nausea and<br />

retching<br />

112. Ether is still used as a general anaesthetic in India,<br />

specially in peripheral hospitals because:<br />

(a) It is non-explosive<br />

(b) It is pleasant smelling and non irritating<br />

(c) It induces anaesthesia rapidly<br />

(d) It is cheap and can be administered without anaesthetic<br />

machine<br />

113. As a general anaesthetic, halothane has the following<br />

advantages EXCEPT:<br />

(a) Very good analgesic action<br />

(b) Non-inflammable and non-explosive<br />

(c) Reasonably rapid induction <strong>of</strong> anaesthesia<br />

(d) Pleasant and non-irritating<br />

114. Malignant hyperthermia is a rare complication <strong>of</strong> the<br />

use <strong>of</strong> the following anaesthetic:<br />

(a) Ketamine<br />

(b) Thiopentone sodium<br />

(c) Halothane<br />

(d) Ether<br />

115. ‘Dissociative anaesthesia’ is produced by:<br />

(a) Ketamine<br />

(b) Fentanyl<br />

(c) Prop<strong>of</strong>ol<br />

(d) Both (a) and (b) are correct<br />

116. Ketamine is the preferred anaesthetic for the following<br />

EXCEPT:<br />

(a) Hypertensives<br />

(b) Trauma cases that have bled significantly<br />

(c) Burn dressing<br />

(d) Short operations on asthmatics<br />

117. If ketamine is the only agent used in reducing a<br />

dislocated shoulder, its actions will include:<br />

(a) Analgesia<br />

(b) Bradycardia<br />

(c) Hypotension<br />

(d) Respiratory depression<br />

118. Postoperative vomiting is uncommon with this<br />

intravenous anaesthetic agent and patients are able<br />

to ambulate sooner than those who receive other<br />

anaesthetic agents:<br />

(a) Ketamine<br />

(b) Enflurane<br />

(c) Prop<strong>of</strong>ol<br />

(d) Remifentanil<br />

119. A young man having pheochromocytoma has BP<br />

<strong>of</strong> 188/92 mm Hg and a hematocrit <strong>of</strong> around 50%.<br />

Pulmonary function tests and renal functions are<br />

normal. His catecholamines are elevated. Which <strong>of</strong><br />

the following drugs should not be included in the<br />

anesthesia protocol?<br />

(a) Desflurane<br />

(b) Fentanyl<br />

(c) Halothane<br />

(d) Midazolam<br />

421<br />

General Anaesthesia <strong>Pharmacology</strong><br />

https://kat.cr/user/Blink99/

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