Review of Pharmacology - 9E (2015)

Autonomic Nervous System
84
Review of Pharmacology
(b) IV adrenaline increases systolic, decreases diastolic
BP and causes tachycardia
(c) IV isoproterenol increases systolic, decreases diastolic
BP and causes tachycardia
(d) Dopamine increases peripheral resistance and improves
renal perfusion
117. Which is not an endogenous catecholamine?
(a) Dopamine (AIIMS May, 2007)
(b) Dobutamine
(c) Adrenaline
(d) Noradrenaline
118. Which of the following is not an alpha adrenoceptor
agonist? (AIIMS May, 2005)
(a) Clonidine
(b) Methyldopa
(c) Guanabenz
(d) Guanfacine
119. Uses of α 2
agonists are all except:
(a) To produce sedation
(b) Glaucoma
(c) Benign hyperplasia of prostate
(d) Hypertension
120. True statement(s) out of the following is/are:
(PGI June, 2001)
(a) β 1
receptors in heart stimulate its contractions
(b) β 2
receptors in heart stimulate its contractions
(c) β 2
receptors are present in smooth muscles
(d) α 1
receptors cause preganglionic stimulation
(e) α 2
receptors cause postganglionic feedback inhibition
121. True about tachyphylaxis is: (PGI Dec. 2006)
(a) Direct sympathomimetics involved
(b) Mechanism clearly understood
(c) Ephedrine tachyphylaxis reversed with dopamine
(d) Indirect sympathomimetics involved
(e) It is an anaphylactic reaction
122. A patient, Harish came to the emergency after receiving
penicillin injection. He was diagnosed to have
anaphylactic shock. Which of the following is the only
life saving measure to treat him?
(a) Intravenous hydrocortisone hemisuccinate
(b) Intravenous adrenaline hydrochloride
(c) Intramuscular adrenaline hydrochloride
(d) Intravenous glucose saline
123. The only non-catecholamine sympathomimetic drug
out of the following is:
(a) Adrenaline
(b) Ephedrine
(c) Dopamine
(d) Isoprenaline
124. Which of the following drugs shows the phenomenon
of vasomotor reversal of Dale after administration of an
α adrenergic blocker?
(a) Adrenaline
(b) Noradrenaline
(c) Isoprenaline
(d) All of the above
125. A drug is shown to activate dopaminergic D 1
and D 2
and adrenergic α and β 1
but not β 2
receptors. Which of
the following can be the drug being talked about?
(a) Dopamine
(b) Dobutamine
(c) Methoxamine
(d) Phenylephrine
126. A patient in shock comes to you in trauma ward. You
examine him and decide not to give him vasoconstrictors.
Which is the type of shock your patient is having?
(a) Neurogenic shock
(b) Haemorrhagic shock
(c) Secondary shock
(d) Hypotension due to spinal anaesthesia
127. The correct statement regarding adrenergic neuron
blocking drugs is:
(a) Block the action of adrenaline on neuronal α 2
adrenoceptors
(b) Block both α and β adrenoceptor mediated effects of
injected adrenaline
(c) Do not block any effect of injected adrenaline
(d) Do not block the effects of sympathetic nerve stimulation
128. A child, Ramu has swallowed the contents of 2 bottles
of a nasal decongestant whose primary ingredient is α
adrenoceptor agonist drug. The signs of α activation
that may occur in this patient include:
(a) Tachycardia
(b) Dilatation of pupil
(c) Vasodilation
(d) All of the above
129. The neurotransmitter agent that is normally released in
the SA node of the heart in response to increased blood
pressure is:
(a) Acetylcholine
(b) Dopamine
(c) Adrenaline
(d) Noradrenaline
130. β 2
selective agonists are often effective in:
(a) Angina due to coronary insufficiency
(b) Asthma
(c) Delayed labour
(d) All the above
131. Which of the following drugs will decrease heart rate
in a patient with a normal heart rate but will have little
effect on heart rate in a cardiac transplant recipient?
(a) Adrenaline
(b) Noradrenaline
(c) Isoproterenol
(d) Phenylephrine
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