Review of Pharmacology - 9E (2015)
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Review of Pharmacology - 9E (2015)

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Endocrinology<br />

276<br />

<strong>Review</strong> <strong>of</strong> <strong>Pharmacology</strong><br />

(c) Cimetidine<br />

(d) Omeprazole<br />

129. In Addison’s disease drug to be given is:<br />

(DBN 2006, DNB 2003, MPPG 2003)<br />

(a) Hydrocortisone<br />

(b) Betamethasone<br />

(c) Prednisolone<br />

(d) DOCA<br />

130. Corticosteroids cause all EXCEPT: (MPPG 2001)<br />

(a) Muscular hypertrophy<br />

(b) Peptic ulceration<br />

(c) Psychosis<br />

(d) Suppression <strong>of</strong> pituitary-adrenal axis<br />

131. Glucocorticoids with mineralocorticoids activity is seen<br />

in: (UP 2006) (UP 2007)<br />

(a) Triamcinolone<br />

(b) Betamethasone<br />

(c) Cortisol<br />

(d) Dexamethosone<br />

132. Which <strong>of</strong> the following antifungal drug can be used in<br />

the treatment <strong>of</strong> Cushing syndrome? (UP 2005)<br />

(a) Ketoconazole<br />

(b) Fluconazole<br />

(c) Itraconazole<br />

(d) Miconazole<br />

133. All <strong>of</strong> the following glucocorticoids lack<br />

mineralocorticoid activity, except: (TN 2007)<br />

(a) Beclomethasone<br />

(b) Triamcinolone<br />

(c) Prednisolone<br />

(d) Dexamethasone<br />

134. All <strong>of</strong> the following are side effects <strong>of</strong> steroids except:<br />

(a) Hyperglycemia (RJ 2000)<br />

(b) Infection<br />

(c) Osteomalacia<br />

(d) Peptic ulcer<br />

135. All are side effects <strong>of</strong> steroids except: (RJ 2002)<br />

(a) Diabetes<br />

(b) Osteoporosis<br />

(c) Fragile skin<br />

(d) Hypotension<br />

136. Anti-inflammatory action <strong>of</strong> corticosteroids is due to<br />

blocking <strong>of</strong>: (RJ 2006)<br />

(a) 15 lipoxygenase<br />

(b) Prostaglandin synthetase<br />

(c) Thromboxane synthetase<br />

(d) Break down <strong>of</strong> phospholipids<br />

137. Which <strong>of</strong> the following is used for medical adre -<br />

nalectomy? (RJ 2009)<br />

(a) Mitotane<br />

(b) Methotrerate<br />

(c) Doxorubicin<br />

(d) 5-Fluorouracil<br />

138. Which <strong>of</strong> the following is the side effect <strong>of</strong> steroids due<br />

to its mineralocorticoid component? (MH 2003)<br />

(a) Skin striae<br />

(b) Hypertension<br />

(c) Osteoporosis<br />

(d) Moon face<br />

139. Side effect <strong>of</strong> steroids are all except: (Bihar 2004)<br />

(a) Hypoglycemia<br />

(b) Hypertension<br />

(c) Psychosis<br />

(d) Growth retardation<br />

140. Which one has least mineralocorticoid activity?<br />

(a) Cortisol (Kolkata 2005)<br />

(b) Prednisolone<br />

(c) Fludrocortisone<br />

(d) Methyl prednisolone<br />

141. Steroids cause: (Kolkata 2005)<br />

(a) Increased TSH<br />

(b) Increased FSH<br />

(c) Prevent de-iodination<br />

(d) All <strong>of</strong> the above<br />

142. In which <strong>of</strong> the following disease is corticosteroids<br />

indicated? (Karnataka 2006)<br />

(a) Osteoporosis<br />

(b) Peptic ulcer<br />

(c) Collagen vascular diseases<br />

(d) Tuberculosis<br />

osteoporosis and calcium metabolism<br />

143. All <strong>of</strong> the following decrease bone resorption in<br />

osteoporosis except: (AI 2011)<br />

(a) Alendronate<br />

(b) Etidronate<br />

(c) Strontium<br />

(d) Teriparatide<br />

144. Which <strong>of</strong> the following drug is a SERM useful for<br />

treatment <strong>of</strong> osteoporosis? (AIIMS Nov, 2010)<br />

(a) Raloxifene<br />

(b) Bisphosphonate<br />

(c) Strontium<br />

(d) Estradiol<br />

145. Both decreased bone resorption and increased bone<br />

formation is caused by: (AIIMS May, 2010)<br />

(a) Strontium ranelate (AIIMS Nov, 2008)<br />

(b) Ibadronate<br />

(c) Teriparatide<br />

(d) Calcitonin<br />

146. Which <strong>of</strong> the following is a serious adverse effect seen<br />

with zolendronate? (DPG 2011)<br />

(a) Acute renal failure<br />

(b) Ventricular fibrillation<br />

(c) Peptic ulcer<br />

(d) Anterior uveitis<br />

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