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Review of Pharmacology - 9E (2015)

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<strong>Review</strong> <strong>of</strong> <strong>Pharmacology</strong><br />

Chemotherapy A: General Considerations and Non-specific...<br />

56. Sulfonamides inhibit bacterial synthesis <strong>of</strong> folic acid<br />

by:<br />

(a) Uncompetitive inhibition<br />

(b) Allosteric inhibition<br />

(c) Competitive inhibition<br />

(d) Non competitive inhibition<br />

57. Which <strong>of</strong> the following drugs is an anti-pseudomonal<br />

penicillin?<br />

(a) Cephalexin<br />

(b) Dicloxacillin<br />

(c) Piperacillin<br />

(d) Cloxacillin<br />

58. Which can be given safely in renal failure?<br />

(a) Tetracycline<br />

(b) Gentamicin<br />

(c) Amphotericin B<br />

(d) Doxycycline<br />

59. Drug <strong>of</strong> choice in pneumonia caused by P carnii is:<br />

(a) Penicillin<br />

(b) Cotrimoxazole<br />

(c) Kanamycin<br />

(d) Lev<strong>of</strong>loxacin<br />

60. Which <strong>of</strong> the following drugs is a 4th generation<br />

cephalosporin?<br />

(a) Cefixime<br />

(b) Ceftriaxone<br />

(c) Cefpirome<br />

(d) Cefazolin<br />

61. Which <strong>of</strong> the following drugs should not be given in<br />

renal failure?<br />

(a) Clindamycin<br />

(b) Methicillin<br />

(c) Amoxicillin<br />

(d) Rifampicin<br />

62. Beta lactam antibiotics are all except:<br />

(a) Amoxicillin<br />

(b) Aztreonam<br />

(c) Ceftriaxone<br />

(d) Vancomycin<br />

63. All <strong>of</strong> the following drugs are administered orally<br />

except:<br />

(a) Cipr<strong>of</strong>loxacin<br />

(b) Cotrimoxazole<br />

(c) Gentamicin<br />

(d) Amoxicillin<br />

64. Aplastic anemia is the adverse effect <strong>of</strong>:<br />

(a) Chloramphenicol<br />

(b) Cipr<strong>of</strong>loxacin<br />

(c) Penicillin<br />

(d) Gentamicin<br />

65. Highest photosensitivity is seen with:<br />

(a) Pefloxacin<br />

(b) Gatifloxacin<br />

(c) Lev<strong>of</strong>loxacin<br />

(d) Sparfloxacin<br />

66. Drug most commonly implicated in causing pseudo<br />

membranous colitis is:<br />

(a) Clindamycin<br />

(b) Streptomycin<br />

(c) Amoxicillin<br />

(d) Metronidazole<br />

67. Which <strong>of</strong> the following is a side effect <strong>of</strong> streptomycin?<br />

(a) Phototoxicity<br />

(b) Hepatotoxicity<br />

(c) Ototoxicity<br />

(d) All <strong>of</strong> the above<br />

68. Not true about vancomycin is:<br />

(a) 95% oral bioavailability<br />

(b) Inhibits cells wall synthesis<br />

(c) Can be used parenterally as well as orally<br />

(d) Indicated for MRSA infections<br />

69. Dosage <strong>of</strong> topical tobramycin eye drops:<br />

(a) 1 mg/ml<br />

(b) 2 mg/ml<br />

(c) 3 mg/ml<br />

(d) 4 mg/ml<br />

70. Route <strong>of</strong> administration <strong>of</strong> vancomycin in pseudomembranous<br />

colitis is:<br />

(a) i.m.<br />

(b) oral<br />

(c) i.v.<br />

(d) s.c.<br />

71. Dosage <strong>of</strong> benzyl penicillin in treatment <strong>of</strong> primary<br />

syphilis is:<br />

(a) 1.2 MU single i.m.<br />

(b) 1.2 MU single i.v.<br />

(c) 2.4 MU single i.m.<br />

(d) 4.8 MU single i.m.<br />

72. Treatment <strong>of</strong> non-specific urethritis is:<br />

(a) Erythromycin<br />

(b) Sulphonamides<br />

(c) Tetracycline<br />

(d) Ampicillin<br />

73. Hemolysis in G-6 deficiency is precipitated by all <strong>of</strong> the<br />

following except:<br />

(a) Dapsone<br />

(b) Cotrimoxazole<br />

(c) Quinine<br />

(d) Penicillin<br />

556<br />

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