Review of Pharmacology - 9E (2015)

Chemotherapy B: Antimicrobials for Specific Conditions
(c) Permethrin
(d) Contrimoxazole
39. Drug resistance in Mycobacterium tuberculosis is due
to:
(a) Conjugation
(b) Transduction
(c) Mutation
(d) None of the above
40. The treatment of choice for bacterial vaginosis is:
(a) Clindamycin
(b) Erythromycin
(c) Ampicillin
(d) Metronidazole
41. The antifungal which has a bactericidal mode of action
against dermatophyte infections in therapeutic doses is:
(a) Fluconazole
(b) Terbinafine
(c) Itraconazole
(d) Ketoconazole
42. Which one of the following is not an antiretroviral
drug:
(a) Saquinavir
(b) Ganciclovir
(c) Indinavir
(d) Atazanavir
43. The drug(s) currently recommended by National AIDS
Control Organization for prevention of mother to child
transmission of HIV infection are:
(a) Zidovudine to mother during pregnancy and labour
and to baby after delivery
(b) Zidovudine and nevirapine to mother during
pregnancy and labour and to baby after delivery
(c) Nevirapine to mother during pregnancy and labour
and to baby after delivery
(d) Zidovudine and lamivudine to mother during
pregnancy and labour and to baby after delivery
44. Drug of choice in herpes simplex encephalitis is:
(a) Acyclovir
(b) Vidarabine
(c) Interferon
(d) Amantadine
45. The other name for reverse transcriptase is:
(a) DNA dependent DNA polymerase
(b) RNA dependent RNA polymerase
(c) DNA dependent RNA polymerase
(d) RNA dependent DNA polymerase
46. First line drug for falciparum malaria in pregnancy is:
(a) Chloroquine
(b) Quinine
(c) Primaquine
(d) Tetracycline
47. Which one of the anti-tubercular drug may precipitate
gout:
(a) Pyrazinamide
(b) Rifampicin
(c) Streptomycin
(d) Isoniazid
48. Which one of the following therapies would be safe in a
patient with pulmonary tuberculosis having markedly
abnormal liver function:
(a) Streptomycin + isoniazid
(b) Ethambutol + isoniazid
(c) Rifampicin + isoniazid
(d) Streptomycin + ethambutol
49. The minimum period required for post-exposure
chemoprophylaxis for HIV is:
(a) 4 weeks
(b) 6 weeks
(c) 8 weeks
(d) 12 weeks
50. Drug of choice for kala-azar is:
(a) Sodium stibogluconate
(b) Amphotericin B
(c) Pentamidine
(d) None of the above
51. Antitubercular drug which should not be given to a
patient having both tuberculosis as well as AIDS is:
(a) INH
(b) Pyrazinamide
(c) Ethambutol
(d) Thiacetazone
52. Which antitubercular drug is bacteriostatic?
(a) INH
(b) Pyrazinamide
(c) Rifampicin
(d) Ethambutol
53. Which antimalarial drug is implicated in causing
hypoglycemia?
(a) Chloroquine
(b) Pyrimethamine
(c) Quinine
(d) Primaquine
54. Metronidazole is effective in all of the following conditions
excxept:
(a) Pseudomembranous colitis
(b) Neurocysticercosis
(c) Giardiasis
(d) Amebic liver abscess
55. Which of the following drugs is not used in the treatment
of leprosy?
(a) Rifampicin
(b) Dapsone
(c) Kanamycin
(d) Clofazimine
56. Fastest acting drug on the lepra bacilli is:
(a) Rifampicin
(b) Dapsone
Chemotherapy B: General Antimicrobials Pharmacology for Specific Conditions
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