Review of Pharmacology - 9E (2015)
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Review of Pharmacology - 9E (2015)

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Autonomic Nervous System<br />

86<br />

<strong>Review</strong> <strong>of</strong> <strong>Pharmacology</strong><br />

146. Which <strong>of</strong> the following is not true about adrenergic<br />

receptors? (DPG 1997)<br />

(a) α 1<br />

receptors are usually presynaptic<br />

(b) β 1<br />

receptors are predominantly found in heart<br />

(c) Noradrenaline stimulates β 1<br />

receptors<br />

(d) α 2<br />

receptor stimulation inhibits transmitter release<br />

147. Drug given in cardiogenic shock is: (MPPG 2003)<br />

(a) Dopamine<br />

(b) Phenylephrine<br />

(c) Atropine<br />

(d) Digoxin<br />

148. Which one <strong>of</strong> the following is a relatively selective a 2<br />

adrenergic blocker with short duration <strong>of</strong> action?<br />

(a) Prazosin (TN 2004)<br />

(b) Yohimbine<br />

(c) Terazosin<br />

(d) Doxazosin<br />

149. Biphasic reaction on blood pressure is seen with the<br />

administration <strong>of</strong>: (TN 2008)<br />

(a) Adrenaline<br />

(b) Nor adrenaline<br />

(c) Dopamine<br />

(d) Dobutamine<br />

150. Major Metabolite <strong>of</strong> noradrenaline in urine is: (RJ 2000)<br />

(a) VMA<br />

(b) HVA<br />

(c) Normetanephrine<br />

(d) Metanephrine<br />

151. Methyl dopa acts on which <strong>of</strong> the following receptor?<br />

(a) α 2<br />

(RJ 2001)<br />

(b) α 1<br />

(c) β 1<br />

(d) D 1<br />

152. Muscle glycolysis is increased by: (RJ 2003)<br />

(a) Epinephrine<br />

(b) Acetylcholine<br />

(c) Histamine<br />

(d) Serotonin<br />

153. Salbutamol is preferred over adrenaline in an asthmatic<br />

due to: (RJ 2005)<br />

(a) β 1<br />

selectivity<br />

(b) β 2<br />

selectivity<br />

(c) α 1<br />

selectivity<br />

(d) None<br />

154. Adrenaline increases all <strong>of</strong> the following blood<br />

pressures significantly except: (RJ 2005)<br />

(a) Systolic<br />

(b) Diastolic<br />

(c) Mean BP<br />

(d) Pulse pressure<br />

155. Most unpleasant side effect <strong>of</strong> salbutamol is: (MH 2002)<br />

(a) Tremors<br />

(b) Hypertension<br />

(c) Rhinorrhoea<br />

(d) Headache<br />

156. Methylphenindate is drug <strong>of</strong> choice for: (MH 2003)<br />

(a) Obsessive compulsive disorder<br />

(b) ADHD (attention deficit hyperkinetic disorder)<br />

(c) Enuresis<br />

(d) Autism<br />

157. Conversion <strong>of</strong> norepinephrine to epinephrine occur<br />

by: (MH 2007)<br />

(a) Methylation<br />

(b) Decarboxylation<br />

(c) Oxidation<br />

(d) Sulphation<br />

158. Which <strong>of</strong> the following statement is not true regarding<br />

dobutamine? (MH 2008)<br />

(a) Agonist <strong>of</strong> D 1<br />

and D 2<br />

receptors<br />

(b) Derivative <strong>of</strong> dopamine<br />

(c) Selective beta-agonistic action<br />

(d) Reduced chances <strong>of</strong> arrhythmia than adrenaline<br />

159. Epinephrine act by stimulating: (Jharkhand 2003)<br />

(a) Adenyl cyclase<br />

(b) Phosohodiestaerse<br />

(c) Phospholipase<br />

(d) None<br />

160. Vasomotor reversal <strong>of</strong> Dale is due to: (Jharkhand 2004)<br />

(a) α blocker<br />

(b) β-blocker<br />

(c) α and β-blocker<br />

(d) None<br />

161. Depression occurs as a side effect due to the use <strong>of</strong>:<br />

(a) Reserpine (AP 2001)<br />

(b) Propanolol<br />

(c) Morphine<br />

(d) Amphetamine<br />

162. Catecholamine action on α-receptors causes: (AP 2002)<br />

(a) Increased atrial contraction<br />

(b) Increased heart rate<br />

(c) Detrusor relaxation<br />

(d) Gastrointestinal sphincter contraction<br />

163. Which is not an endogenous catecholamine? (AP 2003)<br />

(a) Isoprenaline<br />

(b) Dopamine<br />

(c) Noradrenaline<br />

(d) Adrenaline<br />

164. Clonidine has the following attributes except:<br />

(a) Acts on a 2<br />

adrenergic receptors (MP 2009)<br />

(b) Can produce rebound hypertension on abrupt withdrawal<br />

(c) Can Produce CNS stimulation<br />

(d) Inhibits salivation<br />

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