Review of Pharmacology - 9E (2015)

Autonomic Nervous System
82
Review of Pharmacology
(c) Is longer acting
(d) Has weaker antimotion sickness activity
81. A drug ‘X’ belongs to the anticholinergic drug group.
It is primarily used in pre anesthetic medication and
also during surgery. Which of the following can be ‘X’?
(a) Glycopyrrolate
(b) Pipenzolate methyl bromide
(c) Isopropamide
(d) Dicyclomine
82. You are being asked to give your expert opinion
as a toxicologist regarding an effective antidote for
belladonna poisoning. Which of the following agents
would you suggest?
(a) Neostigmine
(b) Physostigmine
(c) Pilocarpine
(d) Methacholine
83. What is the most dangerous effect of belladonna in very
young children?
(a) Dehydration
(b) Hallucination
(c) Hypertension
(d) Hyperthermia
84. Which of the following best describes the mechanism
of action of scopolamine?
(a) Irreversible antagonist at nicotinic receptors
(b) Irreversible antagonist at muscarinic receptors
(c) Reversible antagonist at muscarinic receptors
(d) Reversible antagonist at nicotinic receptors
85. Accepted therapeutic indications for the use of
antimuscarinic drugs include all of the following
except:
(a) Hypertension
(b) Motion sickness
(c) Parkinson’s disease
(d) To produce mydriasis and cycloplegia
86. In which of the following organs, the effect of
atropine on parasympathetic system is of the longest
duration?
(a) Eye
(b) Heart
(c) Salivary glands
(d) Urinary bladder
87. Which is the shortest acting mydriatic? (DPG 2010)
(a) Atropine
(b) Tropicamide
(c) Cyclopentolate
(d) Homatropine
88. Oxybutynin acts by: (DPG 2004)
(a) Nicotine receptor stimulation
(b) Muscarinic receptor stimulation
(c) Muscarinic receptor inhibition
(d) α receptor inhibition
89. Atropine does not cause: (DPG 2004, MPPG 2004)
(a) Increase bowel sound
(b) Decrease bowel sound
(c) Dryness
(d) Tachycardia
90. Atropine poisoning causes all, EXCEPT: (DPG 2003)
(a) Dilated pupil
(b) Excitement
(c) Excessive salivation
(d) Hot skin
91. Which of the following drugs is useful in prophylaxis
of motion sickness? (DPG 2000)
(a) Hyoscine
(b) Metoclopramide
(c) Prochlorperazine
(d) Ondansetron
92. Clinical signs of atropine intoxication are as follows,
EXCEPT: (MPPG 2007)
(a) Decreased bowel sounds
(b) Dry skin
(c) Scarlet flushing of face
(d) Increased bowel sounds
93. Atropine is substituted by phenylephrine to facilitate
fundus examination when: (MPPG 2003)
(a) Mydriasis is required without cycloplegia
(b) Cycloplegia is required
(c) Mydriasis and cycloplegia both are required
(d) Cycloplegia and Mydriasis both are not required
94. Treatment of atropine toxicity is: (MPPG 2003)
(a) 2-Pralidoxime
(b) Naloxone
(c) Flumazenil
(d) Physostigmine
95. Short acting mydriatic used in fundoscopy is:
(a) Atropine (UP 2007, 2006, RJ 2006)
(b) Homatropine
(c) Cyclopentolate
(d) Tropicamide
96. The following drug is a selective blocker (antagonist) of
M1 muscarinic receptors: (TN 2004)
(a) Methacholine
(b) Bethanechol
(c) Methoctramine
(d) Pirenzepine
97. All of the following are anticholinergics, except:
(a) Ipratropium bromide (TN 2007)
(b) Dicyclomine
(c) Atropine
(d) Amphetamine
98. Which of the following drugs has no cycloplegic
action? (MH 2005)
(a) Atropine
(b) Cyclopentolate
https://kat.cr/user/Blink99/