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Review of Pharmacology - 9E (2015)

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Chemotherapy A: General Considerations and Non-specific...<br />

548<br />

<strong>Review</strong> <strong>of</strong> <strong>Pharmacology</strong><br />

145. Drug <strong>of</strong> choice for syphilis in a pregnant lady is:<br />

(a) Penicillin (AI 2012)<br />

(b) Azithromycin<br />

(c) Tetracycline<br />

(d) Ceftriaxone<br />

146. A patient diagnosed as having ventilator associated<br />

pneumonia, is on treatment with ceftriaxone and<br />

amikacin. Culture and sensitivity turned out to be<br />

positive for ESBL producing Klebsiella infection. The<br />

most appropriate next action should be :<br />

(AIIMS Nov 2010)<br />

(a) Continue same antibiotic but at higher dose<br />

(b) Replace ceftazidime for ceftriaxone<br />

(c) Remove amikacin and add quinolone<br />

(d) Change over to imipenem.<br />

147. Which <strong>of</strong> the following antibiotic is used in the<br />

treatment <strong>of</strong> Clostridium difficile associated diarrhea?<br />

(a) Cipr<strong>of</strong>loxacin (Delhi PG - 2011)<br />

(b) Metronidazole<br />

(c) Piperacillin<br />

(d) Clindamycin<br />

148. Which <strong>of</strong> the following drug should not be used to treat<br />

Klebsiella infection? (Delhi PG - 2011)<br />

(a) Ampicillin<br />

(b) Amikacin<br />

(c) Imipenem<br />

(d) Tigecycline<br />

149. Drug <strong>of</strong> choice for chlamydial infection in pregnancy<br />

is: (AI 2010)<br />

(a) Doxycycline<br />

(b) Tetracycline<br />

(c) Erythromycin<br />

(d) Cipr<strong>of</strong>loxacin<br />

150. Which <strong>of</strong> the following drugs is effective against<br />

Pseudomonas infection? (DPG 2009)<br />

(a) Ampicillin<br />

(b) Ceftriaxone<br />

(c) Colistin<br />

(d) Cefixime<br />

151. Drug <strong>of</strong> choice for treatment <strong>of</strong> infection caused by<br />

methicillin resistant Staphylococcus aureus is:<br />

(a) Macrolides (DPG 2009)<br />

(b) Third generation cephalosporins<br />

(c) Carbapenems<br />

(d) Glycopeptides<br />

152. Methicillin resistant Staphylococcus aureus is not<br />

expected to respond to: (DPG 2009)<br />

(a) Aminoglycoside<br />

(b) Lincosamide<br />

(c) Oxazolidinone<br />

(d) Carbapenem<br />

153. Fixed drug eruptions can be seen more frequently with:<br />

(a) Penicillin (DPG 2009)<br />

(b) Sulfonamide<br />

(c) Cetrizine<br />

(d) Roxithromycin<br />

154. Which <strong>of</strong> the following penicillins is effective against<br />

pseudomonas?<br />

(AI-2008)<br />

(a) Piperacillin<br />

(b) Amoxycillin<br />

(c) Ampicillin<br />

(d) Oxacillin<br />

155. Drug <strong>of</strong> choice for prophylaxis <strong>of</strong> diphtheria is:<br />

(a) Tetracycline<br />

(AI-2008)<br />

(b) Erythromycin<br />

(c) Cipr<strong>of</strong>loxacin<br />

(d) Amikacin<br />

156. Which <strong>of</strong> the following is least nephrotoxic? (AI-2008)<br />

(a) Streptomycin<br />

(b) Gentamicin<br />

(c) Polymixin B<br />

(d) Doxycycline<br />

157. Drug commonly used against enteric fever are all<br />

except: (AI 2008)<br />

(a) Amikacin<br />

(b) Cipr<strong>of</strong>loxacin<br />

(c) Ceftriaxone<br />

(d) Azithromycin<br />

158. Which <strong>of</strong> the following is an antipseudomonal anti -<br />

biotic? (AI 2007)<br />

(a) Cipr<strong>of</strong>loxacin<br />

(b) Vancomycin<br />

(c) Cefaclor<br />

(d) Tetracycline<br />

159. Which <strong>of</strong> the following drugs is not used for MRSA?<br />

(a) Cefaclor (AIIMS May 2007, AI 2007)<br />

(b) Cotrimoxazole<br />

(c) Cipr<strong>of</strong>loxacin<br />

(d) Vancomycin<br />

160. Which <strong>of</strong> the following medications is contraindicated<br />

in patients with allergy to sulfonamides? (AI 2006)<br />

(a) Levobunolol<br />

(b) Bimatoprost<br />

(c) Brinzolamide<br />

(d) Brimonidine<br />

161. A diabetic patient develops cellulitis due to Staphylococcus<br />

aureus that was found to be methicillin<br />

resistant on the antibiotic sensitivity testing. All <strong>of</strong> the<br />

following antibiotics will be appropriate EXCEPT:<br />

(a) Vancomycin (AI 2006)<br />

(b) Imipenem<br />

(c) Teicoplanin<br />

(d) Linezolid<br />

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