Review of Pharmacology - 9E (2015)

Review of Pharmacology
Multiple Choice Questions
Respiratory System
476
1. Which of the following drugs can be administered by
subcutaneous route? (AIIMS May 2013)
(a) Albuterol
(b) Terbutaline
(c) Metaproterenol
(d) Pirbuterol
2. Mechanism of acion of theophylline in bronchial asthma is:
(a) Phosphodiesterase 4 inhibition (AI 2010)
(b) Beta2 agonism
(c) Anticholinergic action
(d) Inhibition of mucociliary clearance
3. To prevent exercise induced bronchial asthma drug
used is: (DPG 2009)
(a) Sodium cromoglycate
(b) Ipratropium bromide
(c) Terbutaline
(d) Epinephrine
4. Which of the following drugs has been found to be
useful in acute severe asthma? (DPG 2009)
(a) Magnesium Sulphate
(b) Anti-leukotrine
(c) Cromolyn Sodium
(d) Cyclosporine
5. Leukotriene receptor antagonist used for bronchial
asthma is: (RJ 2008, MH 2007, AI 2007)
(a) Zafirlukast
(b) Zileuton
(c) Cromolyn sodium
(d) Aminophylline
6. Which enzyme is inhibited by aminophylline?
(a) Monoamine oxidase (AI 2006)
(b) Alcohol dehydrogenase
(c) Phosphodiesterase
(d) Cytochrome P 450
7. With which of the following receptors theophylline has
an antagonistic interaction? (AI 2005, UP 2005)
(a) Histamine receptors
(b) Bradykinin receptors
(c) Adenosine receptors
(d) Imidazoline receptors
8. All of the following statements about theophylline are
correct EXCEPT: (AI 2001)
(a) Increase in dose is required in cardiopulmonary disease
(b) Increases cAMP
(c) Increase in dose is required in smokers
(d) Inhibits phosphodiesterase
9. The loading dose of aminophylline is:
(a) 50-75 mg/kg (AIIMS May, 2006)
(b) 0.5-1 mg/kg
(c) 2-3.5 mg/kg
(d) 5-6 mg/kg
10. Which of the following is NOT an adverse effect of
salbutamol? (AIIMS Nov, 2003)
(a) Tachycardia
(b) Tolerance
(c) Hypokalemia
(d) Hypoglycemia
11. Inhibition of 5-lipoxygenase is useful in:
(a) Cardiac failure (AIIMS Nov, 02)
(b) Bronchial asthma
(c) Hepatic failure
(d) Arthritis
12. The drug not used in acute asthma is:
(a) Salbutamol (AIIMS May, 02)
(b) Ipratropium
(c) Montelukast
(d) Hydrocortisone
13. Inflammation in the airways can be reduced by:
(a) Fluticasone (PGI June, 2006)
(b) Budesonide
(c) Theophylline
(d) Salbutamol
(e) Ipratropium
14. True about zafirlukast is: (PGI Dec. 2005)
(a) It inhibit lipooxygenase pathway
(b) It decreases the frequency of asthma attacks as compared
to glucocorticoids
(c) It blocks LT receptor
(d) It is effective in acute bronchial asthma
(e) It can be administered orally
15. Drugs which increase level of theophylline include:
(a) Ciprofloxacin (PGI June, 2002)
(b) Barbiturates
(c) Cimetidine
(d) Allopurinol
(e) Phenytoin
16. Which of the following anti-asthma drugs is not a
bronchodilator?
(a) Ipratropium bromide
(b) Theophylline
(c) Formoterol
(d) Sodium cromoglycate
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