Review of Pharmacology - 9E (2015)

Review of Pharmacology
Respiratory System
17. Which of the following drug is not used in the treatment
of bronchial asthma:
(a) b 2
agonists
(b) Corticosteroids
(c) Cholinesterase inhibitors
(d) Phosphodiesterase inhibitors
18. All of the following are useful in the management of
acute asthma except:
(a) Hydrocortisone intravenously
(b) Salbutamol inhalation
(c) Salmeterol inhalation
(d) Terbutaline inhalation
19. Which of the following drugs prevents the release of
leukotrienes and histamine from mast cells?
(a) Zileuton
(b) Fexofenadine
(c) Nedocromil
(d) Tiotropium
20. Which of the following is a long acting b2 selective
agonist?
(a) Formoterol
(b) Isoprenaline
(c) Salbutamol
(d) Ephedrine
21. In bronchial asthma the mechanism of action of
corticosteroids is:
(a) Relax airway smooth muscle directly
(b) Inhibits mast cell deregulation
(c) Inhibits adenosine receptors
(d) Inhibits lymphocytic eosinophilic mucosal inflammation
22. Leukotrienes inhibitors are very effective in which one
of the following condi tions:
(a) Exercise induced asthma
(b) Antigen induced asthma
(c) Aspirin induced asthma
(d) Occupational asthma
23. Inhaled sodium cromoglycate:
(a) Prevents the antigen antibody combination
(b) May cause cardiac arrhythmias
(c) Is of benefit in preventing exercise induced bronchial
spasm
(d) Is effective in alleviating an acute episode of allergic
asthma
24. Most common side effect of inhalational beclomethasone
is:
(a) Adrenal suppression
(b) Oropharyngeal candidiasis
(c) Bronchoconstriction
(d) Hepatitis
25. Efficacy of inhaled steroids is maximum when particle
size is:
(a) 1-5 µm
(b) 5-10 µm
(c) 10-15 µm
(d) 15-20 µm
26. Zileuton is:
(a) 5 lipooxygenase inhibitor
(b) TX A 2
inhibitor
(c) Leukotriene receptor antagonist
(d) Prostaglandin synthesis inhibitor
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