Review of Pharmacology - 9E (2015)

Review of Pharmacology
COMBINED ALPHA AND BETA BLOCKERS
Labetalol and carvedilol are the important drugs in this group. These are useful for the control of
hypertensive episodes in pheochromocytoma. Carvedilol is the most commonly used beta blocker
in chronic CHF due to its antioxidant and antimitogenic properties. Other drugs having both
α and β blocking activity are medroxalol and bucindolol.
Note: Note: Carvedilol has maximum plasma protein binding (98%) whereas celiprolol has minimum
(< 5%).
Autonomic Nervous System
74
https://kat.cr/user/Blink99/