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Review of Pharmacology - 9E (2015)

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<strong>Review</strong> <strong>of</strong> <strong>Pharmacology</strong><br />

Chemotherapy B: Antimicrobials for Specific Conditions<br />

20. Peripheral neuropathy not caused by which antiretroviral<br />

drug?<br />

(a) Lamivudine<br />

(b) Didanosine<br />

(c) Zidovudine<br />

(d) Zalcitabine<br />

21. Antifungal used as cancer chemotherapeutic agent is:<br />

(a) Flucytosine<br />

(b) Nystatin<br />

(c) Voriconazole<br />

(d) Terbinafine<br />

22. Drug not given for malaria prophylaxis is:<br />

(a) Chloroquine<br />

(b) Proguanil<br />

(c) Doxycycline<br />

(d) Artesunate<br />

23. Which <strong>of</strong> the following is a reverse transcriptase inhibitor?<br />

(a) Ritonavir<br />

(b) Saquanavir<br />

(c) Amprenavir<br />

(d) Ten<strong>of</strong>ovir<br />

24. The most effective antitubercular drug against slow<br />

multiplying intracellular mycobacteria is:<br />

(a) Rifampicin<br />

(b) Isoniazid<br />

(c) Pyrazinamide<br />

(d) Ethambutol<br />

25. Metrifonate is effective against:<br />

(a) Amoebiasis<br />

(b) Leishmaniosis<br />

(c) Schistosomiasis<br />

(d) Giardiasis<br />

26. The drug used to treat acyclovir resistant Herpes Simplex<br />

Virus (HSV) and Varicella Zoster Virus (VZV) infection<br />

is:<br />

(a) Foscarnet<br />

(b) Valacyclovir<br />

(c) Abacavir<br />

(d) Ganciclovir<br />

27. Antimalarial agent safe for use in pregnancy is:<br />

(a) Atovaquone<br />

(b) Pyrimethamine<br />

(c) Primaquine<br />

(d) Proguanil<br />

28. Pancreatitis is a common complication <strong>of</strong> which one <strong>of</strong><br />

the following:<br />

(a) Zidovudine<br />

(b) Didanosine<br />

(c) Zalcitabine<br />

(d) Stavudine<br />

29. Disulfiram like interaction with alcohol is seen with all<br />

<strong>of</strong> the following drugs except:<br />

(a) Metronidazole<br />

(b) Cefoperazone<br />

(c) Grise<strong>of</strong>ulvin<br />

(d) Satranidazole<br />

30. Which vitamin is most likely to be deficient in patients<br />

on treatment with isoniazid:<br />

(a) Vitamin B 1<br />

(b) Vitamin B 2<br />

(c) Vitamin B 6<br />

(d) Vitamin B 12<br />

31. Which one <strong>of</strong> the following drug may be used for prevention<br />

<strong>of</strong> relapse <strong>of</strong> P. vivax infection:<br />

(a) Chloroquine<br />

(b) Primaquine<br />

(c) Atovaquone<br />

(d) Tetracycline<br />

32. All <strong>of</strong> the following are anti HIV agents except:<br />

(a) Ritonavir<br />

(b) Acyclovir<br />

(c) Didanosine<br />

(d) Zidovudine<br />

33. MDR tuberculosis is defined by:<br />

(a) Resistance to all first and second line anti-tubercular<br />

agents<br />

(b) Resistance to any three first line anti-tubercular<br />

agents<br />

(c) Resistance to all first line and any three classes <strong>of</strong><br />

second line anti-tubercular agents<br />

(d) Resistance to isoniazid and rifampicin<br />

34. The infective form <strong>of</strong> malarial parasite is:<br />

(a) Trophozoites<br />

(b) Sporozoites<br />

(c) Hypnozoites<br />

(d) Merozoites<br />

35. Isoniazid induced peripheral neuropathy responds to<br />

administrations <strong>of</strong>:<br />

(a) Pyridoxine<br />

(b) Rib<strong>of</strong>lavin<br />

(c) Thiamine<br />

(d) Cobalamin<br />

36. Which <strong>of</strong> the following anti-tubercular agent does not<br />

cause hepato-toxicity?<br />

(a) Isoniazid<br />

(b) Rifampicin<br />

(c) Ethambutol<br />

(d) Pyrazinamide<br />

37. All <strong>of</strong> the following can cause visual adverse effects<br />

except:<br />

(a) Ethambutol<br />

(b) Rifampicin<br />

(c) Chloroquine<br />

(d) Digoxin<br />

38. Scabies can be effectively treated systemically by:<br />

(a) Psoralens<br />

(b) Ivermectin<br />

616<br />

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