Review of Pharmacology - 9E (2015)

213. In a patient with hypertriglyceridemia and low HDL,
which of the following drug will be best without risk of
myopathy as side effect?(MH PGM-CET 2007) (MH 2008)
(a) Fibric acid derivatives (MH 2007)
(b) Nicotinic acid
(c) Atrovastatin
(d) Clofibrate
214. HDL is specifically increased by: (Kolkata 2007)
(a) Lovastatin
(b) Niacin
(c) Gemfibrozel
(d) Probucol
215. The most potent drugs to reduce plasma cholesterol
level are: (Karnataka 2000)
(a) Plant sterols
(b) Fibrates
(c) Anion exchange resins
(d) Statins
RAAS AND MISCELLANEOUS
216. Which of the following drug is associated with highest
cardiac mortality? (AI 2012)
(a) Rofecoxib
(b) Nicorandil
(c) Losartan
(d) Metoprolol
217. Which of the following drug is used for reversal of
cerebral vasospasm and infarct following subarachnoid
hemorrhage? (AI 2012)
(a) Nimodipine
(b) Amlodipine
(c) Diltiazem
(d) Verapamil
218. Ivabradine is indicated in the management of: (AI 2012)
(a) Congestive heart failure
(b) Angina pectoris
(c) Cardiomyopathy
(d) Irritable bowel syndrome
219. Which of the following statements regarding ACE inhibitors
is TRUE?
(AIIMS May 2008, Nov 2008 May 2011)
(a) These inhibit the conversion of angiotensinogen to
angiotensin-1
(b) Omission of prior diuretic dose decreases the risk of
postural hypotension
(c) Lisinopril is shorter acting than enalapril
(d) These are contra-indicated in diabetic patients.
220. Which of the following is not used in the treatment of
pulmonary hypertension? (AIIMS May 2010)
(a) Calcium channel blockers
(b) Alpha blockers
(c) Prostacyclins
(d) Endothelin receptor antagonists
Cardiovascular System
221. Which of the following drugs is best for reducing proteinuria
in a diabetic patient? (DPG 2011)
(a) Metoprolol
(b) Perindopril
(c) Chlorthiazide
(d) Clonidine
222. Which of the following ACE inhibitor is NOT a prodrug?
(AIIMS Nov 2009)
(a) Fosinopril
(b) Enalapril
(c) Ramipril
(d) Lisinopril
223. A 50 years old male with type 2 diabetes mellitus
is found to have 24 hour urinary albumin of 250 mg.
Which of the following drugs may be used to retard
progression of renal disease? (DPG 2009)
(a) Hydrochlorthiazide
(b) Enalapril
(c) Amiloride
(d) Aspirin
224. Angiotensin II causes all except: (AI 2009)
(a) Stimulates release of ADH
(b) Increases thirst
(c) Vasodilation
(d) Stimulates aldosterone release
225. A man presents with chest pain. ECG shows ST segment
depression in leads V1-V4. Which of the following
should not be given? (AIIMS May 2008)
(a) Beta blocker
(b) Thrombolytic
(c) Morphine
(d) Aspirin
226. All are used for treatment of pulmonary hypertension
EXCEPT: (AIIMS May 2008)
(a) Endothelin receptor antagonists
(b) Phosphodiesterase inhibitors
(c) Calcium channel blockers
(d) Beta blockers
227. Vagal stimulation of heart causes? (AIIMS Nov 2008)
(a) Increased heart rate
(b) Increased RR interval in ECG
(c) Increased cardiac output
(d) Increased force of contraction
228. Angiotensin converting enzyme inhibitors when used
for a long time in patients with hypertension, cause:
(DPG 2009)
(a) Rightward shift in renal pressure-natriuresis curve
(b) Reduction in filtration fraction
(c) Significant increase in heart rate
(d) No change in compliance of large arteries
229. Which of the following treatments is appropriate for
tall peaked T waves, on ECG? (DPG 2009)
(a) Atropine IV
(b) Nitroprusside IV
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General Cardiovascular Pharmacology System
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