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Review of Pharmacology - 9E (2015)

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<strong>Review</strong> <strong>of</strong> <strong>Pharmacology</strong><br />

Respiratory System<br />

34. All <strong>of</strong> the following drugs can precipitate acute attack<br />

<strong>of</strong> asthma EXCEPT: (DPG 1998)<br />

(a) Phenylbutazone<br />

(b) Naproxen<br />

(c) Glucocorticoids<br />

(d) Aspirin<br />

35. Ipratropium bromide used in bronchial asthma, is:<br />

(a) β-Sympothomimetics (UP 2008)<br />

(b) Methylxanthines<br />

(c) Anticholinergics<br />

(d) Mast cell stabilizers<br />

36. Which <strong>of</strong> the following is long acting sympathomimetics<br />

used in bronchial asthma? (UP 2008)<br />

(a) Salbutamol<br />

(b) Terbutaline<br />

(c) Bambuterol<br />

(d) Salmeterol<br />

37. Dextromethorphan is an: (TN 2008)<br />

(a) Antihistaminic<br />

(b) Antitussive<br />

(c) Expectorant<br />

(d) Antiallergic<br />

38. Disodium cromoglycate is used by which <strong>of</strong> the<br />

following routes? (RJ 2001)<br />

(a) Inhalation<br />

(b) Oral<br />

(c) IV<br />

(d) IM<br />

39. Which is a “S<strong>of</strong>t steroid” used in bronchial asthma?<br />

(a) Budesonide (RJ 2008)<br />

(b) Dexamethasone<br />

(c) Ciclesonide<br />

(d) Flunisolide<br />

40. Omalizumab is administered in bronchial asthma by<br />

which route? (RJ 2008)<br />

(a) Oral<br />

(b) Intravenous<br />

(c) Subcutaneous<br />

(d) Aerosol<br />

41. Directly acting cough suppressant is: (MH 2000)<br />

(a) Dextromethorphan<br />

(b) Bromhexine<br />

(c) Actyl cysteine<br />

(d) Carbapentate<br />

42. In a patient <strong>of</strong> chronic asthma on treatment with<br />

theophyline, which <strong>of</strong> the following should not be used<br />

to treat his upper respiratory tract infection?<br />

(a) Ampicillin (MH 2003)<br />

(b) Cephalexin<br />

(c) Erythromycin<br />

(d) All<br />

43. Which <strong>of</strong> the following inhibits theophylline<br />

metabolism? (MH-PGM-CET 2007) (MH 2008)<br />

(a) INH<br />

(b) Grise<strong>of</strong>ulvin<br />

(c) Prednisolone<br />

(d) Cipr<strong>of</strong>loxacin<br />

44. Longest acting b-agonist is: (AP 2000)<br />

(a) Salbutamol<br />

(b) Terbutaline<br />

(c) Salmeterol<br />

(d) Theophylline<br />

45. Complications <strong>of</strong> aerosol steroids use include:<br />

(a) Oral candidiasis (AP 2000)<br />

(b) Cushing’s syndrome<br />

(c) Decreased ACTH<br />

(d) Systemic complications<br />

46. The following drug is contraindicated in bronchial<br />

asthma: (AP 2002)<br />

(a) Propanolol<br />

(b) Ipatropium bromide<br />

(c) Theophylline<br />

(d) Ketotifen<br />

47. Release <strong>of</strong> histamine and leukotrienes from mast cells<br />

is prevented by: (Kolkata 2008, Bihar 2006)<br />

(a) Zileuton<br />

(b) Nedocromil sodium<br />

(c) Zafirlukast<br />

(d) Fex<strong>of</strong>enadine<br />

48. Advantage <strong>of</strong> salmeterol over salbutamol is its:<br />

(a) Shorter duration <strong>of</strong> action (Karnataka 2001)<br />

(b) More potency<br />

(c) Longer duration <strong>of</strong> action<br />

(d) Lesser cardiac effects<br />

49. Interaction <strong>of</strong> theophylline with cipr<strong>of</strong>loxacin is:<br />

(UP 2008)<br />

(a) Cipr<strong>of</strong>loxacin increases theophylline metabolism<br />

(b) Cipr<strong>of</strong>loxacin decreases theophylline metabolism<br />

(c) Theophylline increases cipr<strong>of</strong>loxacin metabolism<br />

(d) Theophylline decreases cipr<strong>of</strong>loxacin metabolism<br />

50. Theophylline overdose causes: (UP 2008)<br />

(a) Bradycardia<br />

(b) Seizures<br />

(c) Drowsiness<br />

(d) Bronchospasm<br />

51. Therapeutic blood range <strong>of</strong> theophylline in microgram<br />

per mililitre is: (UP 2008)<br />

(a) 0-5<br />

(b) 5-10<br />

(c) 5-15<br />

(d) 5-20<br />

478<br />

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