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Review of Pharmacology - 9E (2015)

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3. A 30 year old theatre actress developed few wrinkles on the face. The treating physician advised her to have local<br />

injections <strong>of</strong> a drug. This drug is also indicated in cervical dystonia and other spastic disorders like cerebral palsy. Very<br />

recently, it has also been approved for prophylaxis <strong>of</strong> migraine. The physician warned <strong>of</strong> the drug to cause dry mouth<br />

and blurring <strong>of</strong> vision. The actress searched the compound on internet and found the site <strong>of</strong> action <strong>of</strong> the drug as shown<br />

in the diagram below.<br />

Which <strong>of</strong> the following drug is being talked about?<br />

(a) Hemicholinium<br />

(b) Vesamicol<br />

(c) Botulinum toxin<br />

(d) Physostigmine<br />

4. A 70 year old male developed difficulty in ability to form urinary stream and urgency. On per-rectal examination,<br />

prostate was found to be enlarged. Serum prostate specific antigen was within normal limits. The person is also a<br />

known hypertensive for which he is not taking any drug. The surgeon prescribed him a drug A which can quickly<br />

relieve his urinary problems as well as control his blood pressure. Effect <strong>of</strong> this drug on blood pressure <strong>of</strong> a dog in<br />

experimental set up is shown below. Drug A is likely to be.<br />

(a) Finasteride<br />

(b) Tamsulosin<br />

(c) Doxazosin<br />

(d) Propanolol<br />

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