Review of Pharmacology - 9E (2015)

Cardiovascular System
186
Review of Pharmacology
163. All are dihydropyridines except: (Jharkhand 2006)
(a) Nifedipine
(b) Nimodipine
(c) Verapamil
(d) Felodipine
164. The major clinical use of nimodipine is in:
(a) Hypertension (Karnataka 2006)
(b) Angina pectoris
(c) Subarachnoid haemorrhage
(d) Raynaud’s phenomenon
165. When nitrates are combined with calcium channel
blockers: (Karnataka 2006)
(a) Arterial pressure will decrease
(b) Heart rate will increase
(c) Ejection time will decrease
(d) End-diastolic volume will increase
166. Calcium channel blocker with maximum effect on
conduction in heart is: (DPG 2007)
(a) Phenylamine
(b) Nifedipine
(c) Diltiazem
(d) Verapamil
ARRHYTHMIA
167. All are toxicities seen with amiodarone therapy except:
(a) Pulmonary fibrosis (AIIMS May 2009)
(b) Corneal microdeposits
(c) Cirrhosis of liver
(d) Productive cough
168. True about quinidine is/are: (PGI Dec. 2004)
(a) It increases effective refractory period
(b) Used in hypertension
(c) Causes paradoxical tachycardia
(d) It decreases absolute refractory period
(e) Cinchonism is seen
169. Drug of choice for supraventricular tachycardia is:
(a) Verapamil
(AI-2008)
(b) Diltiazem
(c) Digoxin
(d) Phenytoin
170. Which of the following drugs can cause Torsades’de
pointes?
(AI-2008)
(a) Quinidine
(b) Lignocaine
(c) Esmolol
(d) Flecainide
171. Which of the following is not an adverse effect of
chronic amiodarone therapy? (AI 2004)
(a) Pulmonary Fibrosis (RJ 2007, 2003)
(b) Hypothyroidism
(c) Hyperthyroidism
(d) Systemic lupus erythematosis
172. Which of the following anti-arrhythmic agents does not
belong to class Ic? (AIIMS Nov 2006)
(a) Tocainide
(b) Encainide
(c) Flecainide
(d) Propafenone
173. The following statement is not true about sotalol:
(AIIMS May, 2003)
(a) It is a non-selective beta-blocker
(b) It prolongs action potential duration throughout the
heart
(c) It is excreted through bile following hepatic metabolism
(d) Polymorphic ventricular tachycardia is a common
side-effect
174. In a patient of congenital prolonged QT syndrome
and intermittent Torsades de pointes, which of the
following should be prescribed: (AIIMS Nov, 2001)
(a) Magnesium sulphate
(b) Metoprolol
(c) Cardiac pacing
(d) Isoprenaline
175. Antiarrhythmic drugs causing torsades de pointes are:
(a) Quinidine (PGI June, 2003)
(b) Disopyramide
(c) Procainamide
(d) Lidocaine
(e) Propanolol
176. Urgent treatment of procainamide toxicity is:
(a) Calcium chelation
(b) KCl
(c) Nitroprusside
(d) Sodium lactate
177. All of the following drugs can be used for the chronic
oral treatment of arrhythmia except:
(a) Amiodarone
(b) Esmolol
(c) Quinidine
(d) Verapamil
178. The anti-arrhythmic drug of choice in most of the cases
of acute paroxysmal supraventricular tachycardia is:
(a) Adenosine
(b) Amiodarone
(c) Propanolol
(d) Quinidine
179. Drugs that consistently reduce the potassium repolarising
current and thereby prolong the action potential
duration include all of the following except:
(a) Amiodarone
(b) Lignocaine
(c) Quinidine
(d) Sotalol
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