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Review of Pharmacology - 9E (2015)

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Multiple Choice Questions<br />

Autonomic Nervous System<br />

parasympathomimetics and glaucoma<br />

1. Cholinomimetics are not used in (AIIMS Nov 2013)<br />

(a) Glaucoma<br />

(b) Myasthenia gravis<br />

(c) Post operative atony<br />

(d) Partial heart block<br />

2. Correct match <strong>of</strong> drug and mechanism <strong>of</strong> action is<br />

(AIIMS May 2013)<br />

(a) Brimonidine: Decrease aqueous production<br />

(b) Latanoprost: Carbonic anhydrase inhibitor<br />

(c) Pilocarpine: Increases uvoescleral outflow<br />

(d) Betaxolol: Increases trabecular outflow<br />

3. Cholinomimetic drugs can be used for the treatment <strong>of</strong><br />

all the following conditions EXCEPT: (AIIMS Nov 2012)<br />

(a) Closed angle Glaucoma<br />

(b) Bradycardia<br />

(c) Cobra bite<br />

(d) Myasthenia gravis<br />

4. A patient presents to emergency with pinpoint pupil,<br />

salivation, lacrimation, tremors and red tears. Plasma<br />

cholinesterase level was 30% <strong>of</strong> normal. Most probable<br />

Diagnosis is: (AIIMS May 2012)<br />

(a) Organophospahte poisoning<br />

(b) Dhatura poisoning<br />

(c) Opioid poisoning<br />

(d) Pontine hemorrhage<br />

5. Lid retraction is caused by? (AIIMS Nov 2011)<br />

(a) Bimatoprost<br />

(b) Latanoprost<br />

(c) Brimonidine<br />

(d) Apraclonidine<br />

6. What is the probable diagnosis in a patient with a<br />

dilated pupil not responsive to 1% pilocarpine?<br />

(a) Diabetic 3rd nerve palsy (AIIMS Nov 2011)<br />

(b) Adie’s tonic pupil<br />

(c) Uncal herniation<br />

(d) Pharmacological block<br />

7. Dilator pupillae is supplied by: (AIIMS Nov 2011)<br />

(a) Postganglionic parasympathetic from Edinger Westphal<br />

nucleus<br />

(b) Postganglionic sympathetic from cervical sympathetic<br />

chain<br />

(c) Third cranial nerve<br />

(d) Sympathetic fibres <strong>of</strong> fronto-orbtital branch <strong>of</strong><br />

trigeminal nerve<br />

8. Which <strong>of</strong> the following cranial nerves does not carry<br />

parasympathetic outflow? (AIIMS May 2010)<br />

(a) Oculomotor<br />

(b) Trochlear<br />

(c) Facial<br />

(d) Glossopharyngeal<br />

9. A patient came to the casualty with acute bronchial<br />

asthma after treatment for glaucoma. The probable<br />

drug may be: (Delhi PG 2011)<br />

(a) Timolol<br />

(b) Betaxolol<br />

(c) Latanoprost<br />

(d) Anticholinesterase<br />

10. Which <strong>of</strong> the following drugs should not be given in a<br />

patient with acute angle closure glaucoma: (AI 2009)<br />

(a) Pilocarpine<br />

(b) Clozapine<br />

(c) Fluphenazine<br />

(d) Paroxetine<br />

11. Synaptic transmission in the autonomic ganglion is<br />

usually: (DPG 2009)<br />

(a) Adrenergic<br />

(b) Peptidergic<br />

(c) Cholinergic<br />

(d) Mediated by substance P<br />

12. Which <strong>of</strong> the following cranical nerve does not contain<br />

parasympathetic motor (GVE) fibers?<br />

(a) III (DPG 2009, MPPG 2007)<br />

(b) VI<br />

(c) IX<br />

(d) X<br />

13. Major neurotransmitter released at end organ effectors<br />

<strong>of</strong> the sympathic division <strong>of</strong> the autonomic nervous<br />

system is: (DPG 2009)<br />

(a) Adrenaline<br />

(b) Noradrenaline<br />

(c) Dopamine<br />

(d) Acetylcholine<br />

14. All <strong>of</strong> the following agents are used in glaucoma<br />

treatment, except: (DPG 2009)<br />

(a) Apraclonidine<br />

(b) Timolol<br />

(c) Pilocarpine<br />

(d) Metoprolol<br />

Autonomic General <strong>Pharmacology</strong><br />

Nervous System<br />

77<br />

https://kat.cr/user/Blink99/

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