AMMONIUM SULFATE CAS N°: 7783-20-2

OECD SIDS
AMMONIUM SULFATE
4. ECOTOXICITY ID: 7783-20-2
DATE: 18.04.2006
advantage at higher ammonium sulfate concentrations. Both
sensitive and insensitive strains were found in the primary
and nightsoil sludges, with the sensitive strains
predominating. This explained the operational observations in
several sewage treatment plants concerning the efficacy of
nitrifying bacteria.
Test condition: Ammonium sulfate toxicity information is available for both
sewage treatment microorganisms and for microorganisms found
in soil. The sewage treatment study investigated 14 strains of
Nitrobacter spp. (ammonium oxidising bacteria) isolated from
25 different sludges including three sludges from primary
sewage treatment plants and two sludges from nightsoil
treatment plants. Nitrite production kinetic studies showed
that insensitive strains (those which grew well at 4700 mg/lL
ammonium sulfate) showed Monod growth, while sensitive strains
(those which grew at 94 mg/lL but not at 4700 mg/lL)
followed Haldane kinetics.
Reliability: (2) valid with restrictions
16-JUL-2004 (87)
4.5 Chronic Toxicity to Aquatic Organisms
4.5.1 Chronic Toxicity to Fish
Species:
other: Clarias batrachus
Endpoint:
other: endocrine changes
Exposure period: 12 month
Unit: mg/l Analytical monitoring:
LOEC: = 100
Method:
GLP:
Test substance:
Remark:
Result:
other: see Test Condition
no data
other TS: ammonium sulfate fertilizer, not further specified
In this study the effect of ammonium sulfate on the
histology and histochemistry of the thyrotropes,
lactotropes, corticotropes, and the target organs thyroid
and adrenal were studied. The results were compared with
those seen in metopirone and thiourea treated animals and
also after radiothyroidectomy.
Prolonged exposure of Clarias batrachus to sublethal doses
of ammonium sulfate fertilizer induced marked hypertrophy of
the cortical and medullary cells of the interrenal gland and
inhibition of thyroid function evident from the follicular
hypertrophy, hyperplasia, and reduced colloid content with
correlative histological changes in the pituitary
corticotrophs and thyrotrophs of the experimentals.
The thyrotrophes of the control fish were small, and their
nuclei and nucleoli were less prominent.
Test condition:
124
Results were similar in ammonium sulfate and thiourea
treated fish.
More than 60 Clarias batrachus were bought from the fish
market at Varanasi, and acclimated to the laboratory
conditions for ten days prior to the start of the
experiments.
The fish were divided into three groups of ten each. One
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